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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Mouse monoclonal antibody to DJ-1 [PARK7]: IgG/M-1573-100/100 µg
商品详细Biosensis/Mouse monoclonal antibody to DJ-1 [PARK7]: IgG/M-1573-100/100 µg
Biosensis/Mouse monoclonal antibody to DJ-1 [PARK7]: IgG/M-1573-100/100 µg
Biosensis/Mouse monoclonal antibody to DJ-1 [PARK7]: IgG/M-1573-100/100 µg
商品编号: M-1573-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionProteinDJ-1hasmanyrolesincludingprotectingcellsagainstoxidativestressandcelldeath(Ref:SwissProt).MutationsintheDJ-1genehavebeenassociatedwithrareformsofautosomalrecessiveearly-onsetParkinson"sdisease.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenFulllengthrecombinanthumanDJ-1expressedinandpurifiedfromE.coli.
AntibodyTypemonoclonal
IsotypeIgG1/kappa
Clone4H4
OtherNamesOncogeneDJ1;Parkinsondiseaseprotein7;PARK7;DJ-1
AccessionQ99497PARK7_HUMAN;
ProducedinMouse
ApplicationsWB,IHC/IF.Suggesteddilutionofatleast1:1,000forIHC/IF.Dilutionsof1:10,000orlowerisrecommendedforWB.Thisantibodyrevealsaprominent~21kDabandandstainsmainlyincytoplasmoftissueculturecells.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityTheantibodyreactswitha21kDabandbyWesternblotonwholeHeLacelllysate.Ithasalsobeenusedsuccessfullyforimmunocytochemistry.
SpeciesAgainstHuman,Mouse,Bovine
AntibodyAgainstDJ1[PARK7]
BlastURLClickhere
FormLyophilizedfromPBS.Contains5%trehalose.
AppearanceWhitepowder
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
GeneralReferences1.NagakuboD,TairaT,KitauraH,IkedaM,TamaiK,Iguchi-ArigaSMandArigaHDJ-1,anoveloncogenewhichtransformsmouseNIH3T3cellsincooperationwithras.Biochem.Biophys.Res.Commun.231,509–513(1997).
2.BonifatiV,RizzuP,vanBaren,M.J.,SchaapO,BreedveldGJ,KriegerE,DekkerMC,SquitieriF,IbanezP,JoosseMetal.MutationsintheDJ-1geneassociatedwithautosomalrecessiveearly-onsetParkinsonism.Science,299,256–259(2003).
3.XuJ,ZhongN,WangH,EliasJE,KimCY,WoldmanI,PiflC,GygiSP,GeulaC,YanknerBA.TheParkinson"sdisease-associatedDJ-1proteinisatranscriptionalco-activatorthatprotectsagainstneuronalapoptosis.HumMolGenet.14(9):1231-41(2005).
4.YokotaT,SugawaraK,ItoK,TakahashiR,ArigaH.AndMizusawa,H.DownregulationofDJ-1enhancescelldeathbyoxidativestress,ERstress,andproteasomeinhibition.Biochem.Biophys.Res.Commun.,312,1342–1348(2003).
5.TairaT,SaitoY,NikiT,Iguchi-ArigaSM,TakahashiKandArigaH.DJ-1hasaroleinantioxidativestresstopreventcelldeath.EMBORep.,5,213–218(2004).
6.BonifatiV,OostraBA.andHeutink,P.LinkingDJ-1toneurodegenerationoffersnovelinsightsforunderstandingthepathogenesisofParkinson’sdisease.J.Mol,Med.82,163-174(2004).
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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