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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit polyclonal antibody to Ubiquitin: Whole serum/R-1405-50/50 µl
商品详细Biosensis/Rabbit polyclonal antibody to Ubiquitin: Whole serum/R-1405-50/50 µl
Biosensis/Rabbit polyclonal antibody to Ubiquitin: Whole serum/R-1405-50/50 µl
Biosensis/Rabbit polyclonal antibody to Ubiquitin: Whole serum/R-1405-50/50 µl
商品编号: R-1405-50
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionUbiquitinisahighlyconserved76aminoacidproteinwithanestimatedmolecularweightof8.56kDawhichhasacentralroleinregulatedproteindegradation.Itisaproteinmodifierwhichcanbecovalentlyattachedtotargetlysineseitherasamonomerorasalysine-linkedpolymer.Severaltypesofpolymericchainscanbeformeddependingonthelysineusedfortheassembly.Attachmenttoproteinsasapolymerleadstotheirdegradationbythe26Sproteosome;acomplex,multicatalyticcytosolicandnuclearprotease.Attachmenttoproteinsasamonomerorasanalternativelylinkedpolymerdoesnotleadtoproteasomaldegradationandmayberequiredfornumerousfunctions,includingmaintenanceofchromaticstructure,regulationofgeneexpression,stressresponse,ribosomebiogenesisandDNArepair.Ubiquitinissynthesizedasapolyubiquitinprecursorwithexactheadtotailrepeats,thenumberofrepeatsofwhichdifferbetweenspeciesandstrains.Insomespeciesthereisafinalamino-acidafterthelastrepeat,hereinbovineaCys.Someubiquitingenescontainasinglecopyofubiquitinfusedtoaribosomalprotein(eitherL40orS27a).
BatchNo.Seeproductlabel
Unitsize50µl
AntigenGlutaraldehydecross-linkedubiquitin.
AntibodyTypeAntiserum
OtherNamesRPS27A;UBA52;UBB;UBC;Polyubiquitin-B;Polyubiquitin-C;
AccessionP0CG47UBB_HUMAN;
ProducedinRabbit
ApplicationsWesternBlotting(WB)andImmunohistochemistry(IH).Adilutionof1:5,000-1:10,000isrecommendedforWB.Adilutionof1:500-1,000isrecommendedforIH.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWB.Thisantibodydetects~8.5kDaUbiquitin.
AntibodyAgainstUbiquitin
Cross-reactivityHuman.Predictedtoreactwithothermammaliantissues.
BlastURLClickhere
FormLyophilised
AppearanceWhitepowder
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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