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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit antibody to extracellular superoxide dismutase (SOD3 18-37): whole serum/R-170-100/100 µl
商品详细Biosensis/Rabbit antibody to extracellular superoxide dismutase (SOD3 18-37): whole serum/R-170-100/100 µl
Biosensis/Rabbit antibody to extracellular superoxide dismutase (SOD3 18-37): whole serum/R-170-100/100 µl
Biosensis/Rabbit antibody to extracellular superoxide dismutase (SOD3 18-37): whole serum/R-170-100/100 µl
商品编号: R-170-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionSOD3isamemberofthesuperoxidedismutaseproteinfamily.SODsareantioxidantenzymesthatcatalysethedismutationoftwosuperoxiderADIcalsintohydrogenperoxideandoxygen.SOD3isthoughttoprotectthebrain,lungsandothertissuesfromoxidativestress.Itissecretedintotheextracellularspaceandformsaglycosylatedhomotetramerthatisanchoredtotheextracellularmatrixandcellsurfacesthroughaninteractionwithheparansulfateproteoglycanandcollagen.AsmallpercentageofSOD3iscleavedneartheC-terminusbeforesecretiontogeneratecirculatingtetramersthatdonotinteractwiththeextracellularmatrix.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(WTGEDSAEPNSDSAEWIRD)correspondingtotheaminoacids18-37ofhumanextracellularsuperoxidedismutaseconjugatedtodiphtheriatoxinhasbeenusedastheimmunogen.
OtherNamesEC-SOD;SOD3
AccessionSODE_HUMAN
ProducedinRabbit
PurityWholeserum
ApplicationsIHC,WB.ThisantibodyworkssuperblyinImmunohistochemistryonfrozenorparaffinembeddedtissues.Antigenretrievalhasbeenusedintestingbutmaynotbenecessary.Typicalworkingdilutionsforroutineimmunohistochemistryare1:100to1:2000dependingontissueanddetectionmethod.Forwesternblottingadilutionrangeof1:1000to1:4000isrecommended.Thisantibodystainsprominentlyspecifichumanairway(probablyClaracells)andalveolartypeIIcellsandsometubularcellsinthekidney.Othertissueshavenotyetbeentestedbutthegeneexpressionhasalsobeenreportedinheart,pancreasandplacenta.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThisantibodyhasbeenshowntobespecificforextracellularsuperoxidedismutaseprotein.
Cross-reactivityHuman
BlastitIfyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20°CforahigherstABIlity,andat4°Cwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchase
References1.HjalmarssonK,etal.Proc.Natl.Acad.Sci.U.S.A.84:6340-6344(1987).
2.FolzR.J,etal.Genomics22:162-171(1994).
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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