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Biosensis/Rabbit antibody to mouse superoxide dismutase (SOD1; 24-36): whole serum/R-126-100/100 µl
Biosensis/Rabbit antibody to mouse superoxide dismutase (SOD1; 24-36): whole serum/R-126-100/100 µl
商品编号:
R-126-100
品牌:
Biosensis inc
市场价:
¥5940.00
美元价:
3564.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | FUNCTION:DestroysrADIcalswhicharenormallyproducedwithinthecellsandwhicharetoxictoBIOLOGicalsystems.CATALYTICACTIVITY:2superoxide+2H+=O2+H2O2.COFACTOR:Binds1copperionpersubunit.COFACTOR:Binds1zincionpersubunit.SUBUNIT:Homodimer.SUBCELLULARLOCATION:Cytoplasm.DISEASE:DefectsinSOD1arethecauseoffamilialamyotrophiclateralsclerosis(FALS);alsocalledamyotrophiclateralsclerosis1(ALS1orALS).ALSisadegenerativedisorderofmotorneuronsinthecortex,brainstemandspinalcord.ALSischaracterizedbymuscularweaknessandatrophybeginninginthehandsandspreadingtotheforearmsandlegs.MusclefasciculationsarecommonlyvisIBLe.Sensoryabnormalitiesareabsent.Deathusuallyoccurswithin2to5years.ALSissometimesreferredtoasLouGehrigdiseaseafterthefamousAmericanbaseballplayerwhowasdiagnosedwiththedisorder.FALS,thefamilialformofALS,accountsforabout10%ofthecasesandistransmittedinanautosomaldominantmanner.ThemeanageatonsetofFALSis45years.MISCELLANEOUS:Zincbindingpromotesdimerization.SIMILARITY:BelongstotheCu-Znsuperoxidedismutasefamily. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | Asyntheticpeptide(ASGEPVVLSGQIT)aspartofmousesuperoxidedismutase(SOD1)protein(aa:24-36)conjugatedtodiphtheriatoxoid |
OtherNames | Superoxidedismutase[Cu-Zn];SOD1 |
Accession | SODC_MOUSE |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | WB.Adilutionof1:500to1:1000isrecommendedforthisapplication.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | Specificitywasconfirmedbywesternblotdetectingmousesuperoxidedismutase(SOD1). |
Cross-reactivity | Thisantiserumisknowntoreactwithmouseandratsuperoxidedismutase(SOD1)protein. |
Blastit | Ifyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles. |
SpecificReferences | ParkKHetal.(2013)PostnatalmusclemodificationbymyogenicfactorsmodulatesneuropathologyandsurvivalinanALSmousemodel.NatCommun.2013;4:2906. |
GeneralReferences | 1.JabuschJ.R,etal.Biochemistry19:2310-2316(1980). 2.LevanonD,etal.EMBOJ.4:77-84(1985). 3.HallewellR.A,etal.NucleicAcidsRes.13:2017-2034(1985). 4.ShermanL,etal.Proc.Natl.Acad.Sci.U.S.A.80:5465-5469(1983). 5.KajiharaJ,etal.J.Biochem.104:851-854(1988). 6.AlexanderM.D,etal.Ann.Neurol.52:680-683(2002). 7.GelleraC,etal.Neuromuscul.Disord.11:404-410(2001). 8.MurakamiT,etal.J.Neurol.Sci.189:45-47(2001). 9.PencoS,etal.Neurology53:404-406(1999). 10.MoritaM,etal.Neurosci.Lett.205:79-82(1996). 11.Bartlett,etal.J.NeuroscienceMethods.98(1):63-7(2000) |
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
品牌分类
TR-200-BG型
PE-1243-50型
抗体试剂盒
PE-1246-5型
TR-100-BG型
S-1754-500型
神经营养因子
糖尿病与肥胖
细胞内贩运
电话:PE-1239-5
神经肽和受体
B-100-PS型
受体和通道分子
2个平板ELISA试剂盒
M-1763-100英尺
TR-200-BGT公司
电话:PE-1239-2
PE-1242-5型
M-1249-100号
神经营养因子受体
细胞周期调节器
S-1759-100号
PE-1606-100型
PE-1762-100型
B-200-PS型
PE-019-100型
PE-1241-5型
PE-003-100
1个平板ELISA试剂盒
BL-003-1000型
PE-1246-2型
感觉神经系统
PE-1253-100型
TR-100-FJ
BL-005-500型
神经内分泌
M-1728-100型
DNA损伤与修复
PE-001-100型
PE-1608-1型
TR-400-AG公司
PE-1243-25
细胞标记
PE-1608-5型
TR-100-FJT
自噬
PE-1242-2型
其他神经元
神经递质和酶
抗氧化酶
神经元标志物
标记抗体
BL-004-500型
PE-019-25
PE-1608-10型
BL-002-1250型
受体体嵌合体
信令与转录
基质和粘附分子
BL-001-1250型
癌症
PE-019-500
干细胞
连接蛋白
TR-300-AG型
细胞凋亡
PE-1252-100型
生长因子
发展
阿尔茨海默氏症/帕金森氏症
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