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Biosensis/Rabbit antibody to Peroxiredoxin-6 (NSGPx): whole serum/R-169-100/100 µl
Biosensis/Rabbit antibody to Peroxiredoxin-6 (NSGPx): whole serum/R-169-100/100 µl
商品编号:
R-169-100
品牌:
Biosensis inc
市场价:
¥5940.00
美元价:
3564.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | FUNCTION:Involvedinredoxregulationofthecell.CanreduceH(2)O(2)andshortchainorganic,fattyacid,andphospholipidhydroperoxides.Mayplayaroleintheregulationofphospholipidturnoveraswellasinprotectionagainstoxidativeinjury. SUBUNIT:Homotetramer.SUBCELLULARLOCATION:Cytoplasm.Lysosome.Alsofoundinlungsecretoryorganelles.MISCELLANEOUS:Theactivesiteistheredox-activeCys-47oxidizedtoCys-SOH.Cys-SOHmayrapidlyreactwithaCys-SHoftheothersubunittoformanintermoleculardisulfidewithaconcomitanthomodimerformation.Theenzymemaybesubsequentlyregeneratedbyreductionofthedisulfidebythioredoxin.MISCELLANEOUS:IrreversIBLyinactivatedbyoveroxidationofCys-47(toCys-SO(3)H)uponoxidativestress.SIMILARITY:BelongstotheahpC/TSAfamily.Rehydrinsubfamily. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | RatrecombinantPeroxiredoxin-6.Thesequenceishomologousinhumanandmouseperoxiredoxin-6. |
OtherNames | Non-seleniumglutathioneperoxidase;antioxidantprotein2;1-Cysperoxiredoxin;1-CysPRX;Acidiccalcium-independentphospholipaseA2;NSGPx;Thiol-specificantioxidantprotein;Prdx6;Aipla2;Aop2;Tsa |
Accession | PRDX6_RAT PRDX6_HUMAN PRDX6_MOUSE |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC,WB,ELISA.ThisantibodyworkssuperblyinImmunohistochemistryonfrozenorparaffinembeddedtissues.Antigenretrievalhasbeenusedintestingbutmaynotbenecessary.Typicalworkingdilutionsforroutineimmunohistochemistryare1:100to1:1000dependingontissueanddetectionmethod.Forwesternblottingadilutionrangeof1:1000to1:4000isrecommended.Adilutionof1:1000to1:4000isrecommendedforELISA.Thisantiserumstainsthecytoplasmofepithelialcellsintheratandmouselungandratandhumanbrainastrocytes.ItstainshumanbrainastrocytesinParkinson'sandAlzheimer'sdiseaseandthecentralcoreofsomeLewybodiesinParkinson'sdiseaseanddementiawithLewybodies.Othertissueshavenotyetbeentested.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ThisantibodyhasbeenshowntobespecificforPeroxiredoxin-6protein. |
Cross-reactivity | Rat,humanandmouse,otherspecieshavenotyetbeentested. |
Blastit | Ifyouwouldliketousethisproductinanotherspeicesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20°CforahigherstABIlity,andat4°Cwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles.Glycerol(1:1)maybeaddedforanadditionalstability. |
ExpiryDate | 12monthsafterpurchase |
SpecificReferences | 1.WalshB.etal.(2010)OverexpressionofPrdx6andresistancetoperoxide-induceddeathinHepa1-6cells:Prdxsuppressionincreasesapoptosis.RedoxRep.2009;14(6):275-84. 2.GardinerF.etal.(2010)InductionofPrdx1andPrdx6inLiverCellsbySerumandTPA.IntlJ.Biol.Vol.2,No.1 |
References | 1.KimT.-S,etal.J.Biol.Chem.272:2542-2550(1997). 2.ChoiH.-J,etal.Nat.Struct.Biol.5:400-406(1998). 3.RushJ,etal.Nat.Biotechnol.23:94-101(2005). 4.WagnerE,etal.Biochem.J.366:777-785(2002). 5.ChenJ.-W,etal.J.Biol.Chem.275:28421-28427(2000). 6.KangS.W,etal.J.Biol.Chem.273:6303-6311(1998). 7.GevaertK,etal.Nat.Biotechnol.21:566-569(2003). 8.GregoryS.G,etal.ature441:315-321(2006). 9.NagaseT,etal.DNARes.2:37-43(1995). 10.FrankS,etal.Oncogene14:915-921(1997). 11.PowerJ,etal.AmJ.Path.161:885-894(2202). 12.PowerJ,etal.ExperimentalLungRes.25:379-391(1999). |
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
品牌分类
TR-200-BG型
PE-1243-50型
抗体试剂盒
PE-1246-5型
TR-100-BG型
S-1754-500型
神经营养因子
糖尿病与肥胖
细胞内贩运
电话:PE-1239-5
神经肽和受体
B-100-PS型
受体和通道分子
2个平板ELISA试剂盒
M-1763-100英尺
TR-200-BGT公司
电话:PE-1239-2
PE-1242-5型
M-1249-100号
神经营养因子受体
细胞周期调节器
S-1759-100号
PE-1606-100型
PE-1762-100型
B-200-PS型
PE-019-100型
PE-1241-5型
PE-003-100
1个平板ELISA试剂盒
BL-003-1000型
PE-1246-2型
感觉神经系统
PE-1253-100型
TR-100-FJ
BL-005-500型
神经内分泌
M-1728-100型
DNA损伤与修复
PE-001-100型
PE-1608-1型
TR-400-AG公司
PE-1243-25
细胞标记
PE-1608-5型
TR-100-FJT
自噬
PE-1242-2型
其他神经元
神经递质和酶
抗氧化酶
神经元标志物
标记抗体
BL-004-500型
PE-019-25
PE-1608-10型
BL-002-1250型
受体体嵌合体
信令与转录
基质和粘附分子
BL-001-1250型
癌症
PE-019-500
干细胞
连接蛋白
TR-300-AG型
细胞凋亡
PE-1252-100型
生长因子
发展
阿尔茨海默氏症/帕金森氏症
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