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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit polyclonal antibody to human Cyclooxygenase-2 (28-50): Affinity purified/R-1114-100/100 µg
商品详细Biosensis/Rabbit polyclonal antibody to human Cyclooxygenase-2 (28-50): Affinity purified/R-1114-100/100 µg
Biosensis/Rabbit polyclonal antibody to human Cyclooxygenase-2 (28-50): Affinity purified/R-1114-100/100 µg
Biosensis/Rabbit polyclonal antibody to human Cyclooxygenase-2 (28-50): Affinity purified/R-1114-100/100 µg
商品编号: R-1114-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionCyclooxygenase(COX)isanimportantenzymeintheconversionofarachidonicacidtoProstaglandinH2,theprecursoroftheseries-2prostanoids.Atleast3splicevariantshavebeenfound;COX-1,COX-2andCOX-3.COX-2isinducedbycytokinesandmitogensandisthoughttoplayaroleininflammatorydiseasessuchasrheumatoidarthritis.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenAsyntheticpeptide(NRGVCMSVGFDQYKCDCTRTGFY)correspondingtoaregion(28-50)fromhumanCyclooxygenase-2.Toenhancetheimmunologicalresponse,thispeptidewascoupledtocarrierproteinBSA.
OtherNamesProstaglandinG/Hsynthase2;EC1.14.99.1;Cyclooxygenase-2;COX-2;Prostaglandin-endoperoxidesynthase2;ProstaglandinH2synthase2;PGHsynthase2;PGHS-2;PHSII;PTGS2;COX2;
AccessionP35354PGH2_HUMAN;
ProducedinRabbit
PurityAffinitypurifiedonantigencolumn
ApplicationsImmunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof1.0µg/mlisrecommendedforWB.HumanCOX-2(precursor)hasapredictedlengthof604residuesandMWof69kDa.Aconcentrationof1.0-2.0µg/mlisrecommendedtodetecttheproteininformalinfixedandparaffinembeddedtissues.Heatactivatedantigenretrievalisrequired.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen.
Cross-reactivityHuman;rat;predictedtoreactwithmouseduetosequencehomology;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3
ReconstitutionReconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles
ExpiryDate12monthsafterpurchase
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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