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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit polyclonal antibody to Caspase-3 (207-220): Affinity purified/R-1344-100/100 µg
商品详细Biosensis/Rabbit polyclonal antibody to Caspase-3 (207-220): Affinity purified/R-1344-100/100 µg
Biosensis/Rabbit polyclonal antibody to Caspase-3 (207-220): Affinity purified/R-1344-100/100 µg
Biosensis/Rabbit polyclonal antibody to Caspase-3 (207-220): Affinity purified/R-1344-100/100 µg
商品编号: R-1344-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
Caspase-3isinvolvedintheactivationcascadeofcaspasesresponsIBLeforapoptosis(Ref:SWISSPROT).Recentobservationsinmicrogliahaveimplicatedcaspase3asamodulatorofmicroglialactivationinabsenceofcelldeath.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenAsyntheticpeptide(RNSKDGSWFIQSLC)correspondingtoaregion(207-220aa)fromtheC-terminusofhumanCaspase-3.
SequenceRNSKDGSWFIQSLC
AntibodyTypeAntiserum
OtherNamesCASP-3;Apopain;CysteineproteaseCPP32;CPP-32;ProteinYama;SREBPcleavageactivity1;SCA-1;CASP3;CPP32;
AccessionP42574CASP3_HUMAN;
ProducedinRabbit
ApplicationsWesternBlotting(WB).Aconcentrationof1.0µg/mlisrecommendedforWB.HumanCaspase-3protein(precursor)hasapredictedlengthof277aminoacidsandMWof32kDa.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBagainsttheantigen.
AntibodyAgainstCaspase-3
Cross-reactivityHuman;rat;predictedtoreactwithmouseduetosequencehomology;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenproteins.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
BlastURLClickhere
FormLyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3
AppearanceLyophilizedwhitepowder
ReconstitutionReconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
References1.BurguillosM.A.Caspasesignallingcontrolsmicrogliaactivationandneurotoxicity.Nature.2011Apr21;472(7343):319-24.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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