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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit polyclonal antibody to human Lamin A + C (451-468): Affinity purified/R-1069-100/100 µg
商品详细Biosensis/Rabbit polyclonal antibody to human Lamin A + C (451-468): Affinity purified/R-1069-100/100 µg
Biosensis/Rabbit polyclonal antibody to human Lamin A + C (451-468): Affinity purified/R-1069-100/100 µg
Biosensis/Rabbit polyclonal antibody to human Lamin A + C (451-468): Affinity purified/R-1069-100/100 µg
商品编号: R-1069-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description Lamins belong to the intermediate filament family of proteins. They are structural components of the nuclear lamina and are thought to be involved in nuclear stability, chromatin structure and gene expression. There are two main types of lamins; A and B. Alternative splicing of the Type A lamin gene produces at least 2 isoforms; Lamin A and Lamin C.
Batch No. See product label
Unit size 100 µg
Antigen A synthetic peptide (FVRLRNKSNEDQSMGNWQ) corresponding to amino acids 451-468 from human Lamin A and Lamin C. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
Other Names 70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1;
Accession P02545 LMNA_HUMAN;
Produced in Rabbit
Purity Affinity purified on antigen column
Applications Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 2.0 µg/ml is recommended for WB. Human Lamin A has a predicted length of 664 residues and MW of 74 kDa. Human Lamin C has a predicted length of 572 residues and MW of 65 kDa. A concentration of 1.0-2.0 µg/ml is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen.
Cross-reactivity Human; mouse; rat;
Blast it If you wish to use this product in a species other than those specified here and want to determine the amino acid sequence homology between the immunogen and the corresponding protein in that species, simply copy the amino acid sequence for this immunogen and test it on the BLAST database that you can access through the link below. Please note that antibodies raised against synthetic peptides are quite often very specific for that peptide. What this means in practise is that a single amino acid difference may be enough to restrict the specificity to a particular molecule. The BLAST database can also be used to compare any amino acid sequence between species and between protein. The full amino acid sequence of the target protein can be found by following the link in the Accession field. You can then search any amino acid sequence in the target protein using the BLAST database. When selecting a sequence to search, please choose carefully, as the sequence you choose may be a precursor rather than the mature protein for example.
Form Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Reconstitution Reconstitute in 100 µl of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material.
Storage At least 12 months after purchase at 2 - 4°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
Expiry Date 12 months after purchase
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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