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当前位置: 首页 > 产品中心 > Other_recombinant_protein > 生物传感器/小鼠抗微管相关蛋白2(MAP2)[5H11]:IgG/M-1625-100/100µl
商品详细生物传感器/小鼠抗微管相关蛋白2(MAP2)[5H11]:IgG/M-1625-100/100µl
生物传感器/小鼠抗微管相关蛋白2(MAP2)[5H11]:IgG/M-1625-100/100µl
生物传感器/小鼠抗微管相关蛋白2(MAP2)[5H11]:IgG/M-1625-100/100µl
商品编号: M-1625-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionMicrotubulesare25nmdiameterproteinrodsfoundinmostkindsofeukaryoticcells.Theyarepolymerizedfromadimericsubunitmadeofone"a"subunitandone"b"tubulinsubunit.Microtubulesareassociatedwithafamilyofproteinscalledmicrotubuleassociatedproteins(MAPs),whichincludestheproteint(tau)andagroupofproteinsreferredtoasMAP1,MAP2,MAP3,MAP4andMAP5.MAP2ismadeupoftwo~280kDaapparentmolecularweightbandsreferredtoasMAP2aandMAP2b.Athirdlowermolecularweightform,usuallycalledMAP2c,correspondstoapairofproteinbandsrunningat~70kDaonSDS-PAGEgels.AlltheseMAP2formsarederivedfromasinglegenebyalternatetranscription,andallshareaC-terminalsequencewhichincludeseitherthreeorfourmicrotubulebindingpeptidesequences,whichareverysimilartothosefoundintherelatedmicrotubulebindingproteint(tau).MAP2isoformsareexpressedonlyinneuronalcellsandspecificallyintheperikaryaanddendritesofthesecells.AntibodiestoMAP2arethereforeexcellentMarkersonneuronalcells,theirperikaryaandneuronaldendrites.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenHighmolecularMAPproteinpreparationderivedfrombovinebrain
Clone5H11
OtherNamesMicrotubule-associatedprotein2;MAP-2;Mtap2;
AccessionQ0IIA8MAP2_Bovine
ProducedinMouse
MolecularWeighthttp://http://www.uniprot.org/uniprot/Q0IIA8
PurityIgG
ApplicationsImmunohistochemistry(IHC)andWesternBlotting(WB).Adilutionof1:5,000-1:10,000isrecommendedforWB.Adilutionof1:500-1:1000isrecommendedforIHC.Theoptimaldilutionshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen.
Cross-reactivityHuman;Rat;Mouse;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilizedfromPBS.
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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