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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/针对MAP1LC3A(11-23)的小鼠单克隆抗体[克隆BS405]:IgG/M-1725-100/100µg
商品详细Biosensis/针对MAP1LC3A(11-23)的小鼠单克隆抗体[克隆BS405]:IgG/M-1725-100/100µg
Biosensis/针对MAP1LC3A(11-23)的小鼠单克隆抗体[克隆BS405]:IgG/M-1725-100/100µg
Biosensis/针对MAP1LC3A(11-23)的小鼠单克隆抗体[克隆BS405]:IgG/M-1725-100/100µg
商品编号: M-1725-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionMAP1AandMAP1Baremicrotubule-associatedproteinwhichmediatethephysicalinteractionsbetweenmicrotubulesandcomponentsoftheCytoskeleton(probablyinvolvedinautophagosomeformation).MAP1AandMAP1Beachconsistofaheavychainsubunitand3differentlightchainsubunits(LC1,LC2andLC3).MAP1LC3AisoneofthelightchainsubunitsandcanassociatewitheitherMAP1AorMAP1B.TheprecursorformofMAP1LC3AiscleavedbyAPG4/ATG4BtoformthecytosolicformLC3-1.ThisisactivatedbyAPG7L/ATG7,transferredtoATG3andconjugatedtophospholipidtoformthemembrane-boundform,LC3-II.MAP1LC3Aismostabundantinheart,brain,liver,skeletalmuscleandtestisbutisabsentinthymusandperipheralleukocytes.
BatchNo.Pleaserefertotheproductlabel.
Unitsize100µg
AntigenAsyntheticpeptide(C-RSFADRCKEVQQI)correspondingtoaminoacids11-23ofhumanMAP1LC3Aproteinwasconjugatedtoacarrierproteinandthecomplexusedastheimmunogen.ThishumansequenceishomologouswithmouseandratMAP1LC3A.
SequenceRSFADRCKEVQQI
AntigenLocationIntracellular,cytosolic
AntigenLength13aminoacids
AntibodyTypeMousemonoclonalIgG
IsotypeIgG2a,k-lightchain
CloneBS405
OtherNamesMicrotubule-associatedproteins1A/1Blightchain3A;MAP1A/MAP1BLC3A;MAP1A/1Blightchain3A;MAP1lightchain3-likeprotein1;Microtubule-associatedprotein1lightchain3alpha;Autophagy-relatedproteinLC3A;Autophagy-relatedubiquitin-likemodifierLC3A;APG8a;MAP1LC3A
AccessionMLP3A_HUMAN
MLP3A_MOUSE
MLP3A_RAT
ProducedinMouse
MolecularWeightThebroadbandseenonWBindicatestheantibodydetectsboththecytosolicLC3-Iandautophagosomemembrane-boundLC3-IIformswithapparentmolecularweightsof~14kDa(LC3-I)and~12kDa(LC3-II).
PurityProteinGpurifiedmouseimmunoglobulin
ApplicationsFlowCytometry(20µg/mL),Westernblot(10µg/mL),Immunocytochemistry(1-2µg/mL).Otherapplicationshavenotyetbeentested.Biosensisrecommendsoptimaldilutionsandconcentrationsshouldbedeterminedbytheenduser.
SpecificityWBconfirmedbindingoftheantibodytoabroadproteinbandwithaMolecularWeightof~14kDa.
SpeciesAgainstHuman
Cross-reactivityRat.TheantibodyisexpectedtoreactwithmouseMAP1LC3Aproteindueto100%sequencehomology.
FormLyophilizedfromPBS,pH7.4,containing3%trehalosewithoutpreservatives.
ReconstitutionReconstitutein100µLofsterilewater.Centrifugetoremoveanyinsolublematerial.Finalbuffercontainsnopreservatives.
StorageAfterreconstitutiondivideintoaliquotsandstoreat-20ºCforahigherstABIlity.Antibodycontainsnopreservatives.Storeat4ºCwithanappropriateantibacterialagent.Usesterilemethods.HighestpurityGlycerol(1:1)maybeaddedforanadditionalstabilitywhenstoredatrefrigeratedorfreezingtemperatures.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchaseifunopened.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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