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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit antibody to ATG3: whole serum/R-159-100/100 µl
商品详细Biosensis/Rabbit antibody to ATG3: whole serum/R-159-100/100 µl
Biosensis/Rabbit antibody to ATG3: whole serum/R-159-100/100 µl
Biosensis/Rabbit antibody to ATG3: whole serum/R-159-100/100 µl
商品编号: R-159-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionFUNCTION:GABARAPL1(GABARAPL2orGABARAPorMAP1LC3)-modifierproteinconjugatingenzymeinvolvedinitsE2-likecovalentbindingtoPE.ATG7(E1-likeenzyme)facilitatesthisreactionbyforminganE1-E2complexwithATG3(E2-likeenzyme).PreferredsubstrateisMAP1LC3A.FormationoftheGABARAPL1-PEconjugateisessentialforautophagy.SUBUNIT:InteractswithATG7andATG12.Thecomplex,composedofATG3andATG7,playsaroleintheconjugationofATG12toATG5.SUBCELLULARLOCATION:Cytoplasm.ALTERNATIVEPRODUCTS:2namedisoformsproducedbyalternativesplicing.TISSUESPECIFICITY:Widelyexpressed,withahighestexpressioninheart,skeletalmuscle,kidney,liverandplacenta.SIMILARITY:BelongstotheATG3family.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptidecorrespondingtoacentralregionofthehumanATG3proteinconjugatedtoBlueCarrierProteinhasbeenusedastheimmunogen.ThepeptideishomologouswiththecorrespondingsequencederivedfromATG3proteininmouse,rat,S.cerevisiae,Macacamulatta(monkey)andCanisfamiliaris(dog).
OtherNamesAutophagy-relatedprotein3;APG3;APG3-like;hApg3;ProteinPC3-96;ATG3;APG3;APG3L
AccessionATG3_HUMAN
ATG3_MOUSE
ATG3_RAT
ATG3_Saccharomycescerevisiae
ATG3_Macacamulatta
ATG3_Canisfamiliaris
ProducedinRabbit
PurityWholeserum
ApplicationsIHC,WB,immunofluorescence.Adilutionof1:50to1:3000dilutionisrecommendedfortheseapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityIHC,WBandELISAconfirmedthespecificityforATG3.A37kDaband,thatcorrespondstothemolecularweightofATG3,isdetectedviawesternblotanalysis.
Cross-reactivityHuman,rat,mouse.Otherspeciesnotyettested.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchase
SpecificReferences1.RyningenAetal(2012)InhibitionofMammaliantargetofrapamycininhumanacutemyeloidleukemiacellshasdiverseeffectsthatdependontheenvironmentalinvitrostress.BoneMarrowRes.2012;2012:329061.
References1.TanidaI,etal.J.Biol.Chem.277:13739-13744(2002).
2.OtaT,etal.Nat.Genet.36:40-45(2004).
3.RushJ,etal.Nat.Biotechnol.23:94-101(2005).
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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