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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit antibody to ATG4C (APG4C): whole serum/R-156-100/100 µl
商品详细Biosensis/Rabbit antibody to ATG4C (APG4C): whole serum/R-156-100/100 µl
Biosensis/Rabbit antibody to ATG4C (APG4C): whole serum/R-156-100/100 µl
Biosensis/Rabbit antibody to ATG4C (APG4C): whole serum/R-156-100/100 µl
商品编号: R-156-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionFUNCTION:Cysteineproteaserequiredforautophagy,whichcleavestheC-terminalpartofeitherMAP1LC3,GABARAPL2orGABARAP,allowingtheliberationofformI.AsubpopulationofformIissubsequentlyconvertedtoasmallerform(formII).FormII,witharevealedC-terminalglycine,isconsideredtobethephosphatidylethanolamine(PE)-conjugatedform,andhasthecapacityforthebindingtoautophagosomes.ENZYMEREGULATION:InhibitedbyN-ethylmaleimide.SUBCELLULARLOCATION:Cytoplasm(Probable). SIMILARITY:BelongstothepeptidaseC54family.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(CTVYNSDVIDKQ)correspondingtotheC-terminalofhumanATG4CproteinconjugatedtoBlueCarrierProteinhasbeenusedastheimmunogen.ThepeptideishomologouswiththecorrespondingsequencederivedfromATG4Cproteininmouseandrat.
OtherNamesCysteineproteaseATG4C;Autophagy-relatedprotein4homologC;Autophagin-3;Autophagy-relatedcysteineendopeptidase3;AUT-like3cysteineendopeptidase;ATG4C;APG4C;AUTL3;
AccessionATG4C_HUMAN
ATG4C_MOUSE
ATG4C_RAT
ProducedinRabbit
PurityWholeserum
ApplicationsIHC,immunofluorescenceandWB.Adilutionof1:100to1:2000dilutionisrecommendedfortheseapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityIHC,ELISAandWBconfirmedthespecificityforATG4C.
Cross-reactivityHuman,rat.Otherspeciesnotyettested.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDateSixmonthsafterpurchase
SpecificReferencesSmuderAJetal.(2011)Exerciseprotectsagainstdoxorubicin-inducedMarkersofautophagysignalinginskeletalmuscle.JApplPhysiol(1985).2011Oct;111(4):1190-8.
GeneralReferences1.MarinoG,etal.J.Biol.Chem.278:3671-3678(2003).
2.OtaT,etal.Nat.Genet.36:40-45(2004).
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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