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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Mouse monoclonal antibody to P Glycoprotein [PG-13]: IgG/M-1214-100/100 µg
商品详细Biosensis/Mouse monoclonal antibody to P Glycoprotein [PG-13]: IgG/M-1214-100/100 µg
Biosensis/Mouse monoclonal antibody to P Glycoprotein [PG-13]: IgG/M-1214-100/100 µg
Biosensis/Mouse monoclonal antibody to P Glycoprotein [PG-13]: IgG/M-1214-100/100 µg
商品编号: M-1214-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionPGlycoproteinbelongstotheMDR/TAPsubfamilyofATP-bindingcassette(ABC)transporters.PGlycoproteinisanATP-dependentdrugeffluxpumpexpressedinliver,kidney,smallintestineandbrain.ItisresponsIBLefordecreaseddrugaccumulationinmultidrug-resistantcells.GeneticvariationinPGlycoproteinisthoughttoplayaroleinpatientswhodonotrespondtodrugtreatment.PGlycoproteinalsofunctionsasatransporterintheblood-brainbarrier.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenHumanandhamsterdrug-resistantwholecellsandcrudeplasmamembranes
ClonePG-13
OtherNamesMultidrugresistanceprotein1;ATP-bindingcassettesub-familyBmember1;P-glycoprotein1;CD243;ABCB1;MDR1;PGY1;
AccessionP08183MDR1_HUMAN;
ProducedinMouse
PurityIgG1
ApplicationsImmunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof0.5-1.0µg/mlisrecommendedforWB.HumanPGlycoproteinhasapredictedlengthof1280residuesandMWof141kDa.Aconcentrationof1.0-2.0µg/mlisrecommendedforIHCtodetecttheproteininformalinfixedandparaffinembeddedtissues.Heatmediatedantigenretrievalisrequired.Aconcentrationof1.0-2.0µg/mlisrecommendedforIHCtodetecttheproteininformalin/acetonefixedfrozentissues.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen.
Cross-reactivityHuman;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilizedfrom1.2%sodiumacetate,2mgBSA,0.01mgNaN3
ReconstitutionReconstitutein1mlofPBS(pH7.4)toachieveanantibodyconcentrationof100µg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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