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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit polyclonal antibody to human Matrix metalloproteinase-2 (138-153): Affinity purified/R-1735-100/100 µg
商品详细Biosensis/Rabbit polyclonal antibody to human Matrix metalloproteinase-2 (138-153): Affinity purified/R-1735-100/100 µg
Biosensis/Rabbit polyclonal antibody to human Matrix metalloproteinase-2 (138-153): Affinity purified/R-1735-100/100 µg
Biosensis/Rabbit polyclonal antibody to human Matrix metalloproteinase-2 (138-153): Affinity purified/R-1735-100/100 µg
商品编号: R-1735-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionThematrixmetalloproteinases(MMPs)arealargefamilyof zincendopeptidases.AllMMPsaresynthesizedasinactiveproenzymes.TheactivationoftheseproenzymesisacriticalstepthatleadstodegradationofextracellularmatrixcomponentssuchasfibronectinandcollagentypeIII.MMP2isactivatedbyotherMMPssuchasMMP14andMMP16.MMP2isknowntodegradecollagentypesIV,V,VIIandXaswellasgelatintypeI.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenAsyntheticpeptidecorrespondingtoaregion(138-153)attheN-terminusfromhumanMatrixmetalloproteinase-2.
AntibodyTypeRabbitpolyclonal,affinitypurified
OtherNames72kDatypeIVCollagenase;EC3.4.24.24;72kDagelatinase;Matrixmetalloproteinase-2;MMP-2;GelatinaseA;TBE-1;MMP2;CLG4A;
AccessionP08253MMP2_HUMAN;
ProducedinRabbit
MolecularWeightHumanMMP2(precursor)hasapredictedlengthof660residuesandMWof74kDa.
CompoundName72kDatypeIVcollagenase
PurityAffinitypurifiedonimmunogencolumn
ApplicationsWesternBlotting(WB)andImmunohistochemistry(IHC-PandIHC-F).Aconcentrationof0.1-0.5µg/mlisrecommendedforWB.Aconcentrationof0.5-1µg/mlisrecommendedforIHC(paraffinandfrozensections).Boilingtheparaffinsectionsin10mMcitratebuffer,pH6.0,for20minsisrequiredforthestainingofformalin/paraffinsections.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen.
Cross-reactivityTestedforhuman(WB,IHCparaffinsections),rat(WB,IHCparaffinandfrozensections)andmouse(IHCparaffinandfrozensections).
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3
ReconstitutionSpinvialbrieflybeforeopening.Reconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial.
StorageStoreat-20°C(lyophilizedformulations).Afterreconstitution,storeat2-8°Cshort-term(1month).Aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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