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当前位置: 首页 > 产品中心 > Polyclonal_antibody > Biosensis/兔CD44多克隆(aa728-742)/吞噬糖蛋白1/PGP-1:亲和纯化IgG/R-1721-100/100µg
商品详细Biosensis/兔CD44多克隆(aa728-742)/吞噬糖蛋白1/PGP-1:亲和纯化IgG/R-1721-100/100µg
Biosensis/兔CD44多克隆(aa728-742)/吞噬糖蛋白1/PGP-1:亲和纯化IgG/R-1721-100/100µg
Biosensis/兔CD44多克隆(aa728-742)/吞噬糖蛋白1/PGP-1:亲和纯化IgG/R-1721-100/100µg
商品编号: R-1721-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 多克隆抗体
公司分类: Polyclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionTheproteinidentifiedasCD44isalsoknownasthereceptorforhyaluronicacid(HA).Theproteinmediatescell-cellandcell-matrixinteractionsthroughitsaffinityforHA,andpossIBLyalsothroughitsaffinityforotherligandssuchasosteopontin,collagens,andmatrixmetalloproteinases(MMPs).AdhesionwithHAplaysanimportantroleincellmigration,tumorgrowthandprogression.Incancercells,CD44mayplayanimportantroleininvadopodiaformation,anditalsoisinvolvedinlymphocyteactivation,recirculationandhoming,andinhematopoiesis.AlteredexpressionordysfunctionofCD44causesnumerouspathogenicphenotypes.CD44hasgreatproteinheterogeneityduetonumerousalternativesplicingandpost-translationalmodificationevents.Biosensis"anti-CD44rabbitpolyclonalantibodyisanewantibodymadeagainstasyntheticpeptideepitopeneartheveryC-terminus,cytoplasmicdomainofhumanCD44.Theantibodyhasbeenshowntoreactwithmultiplespeciesincludinghuman,mouseandrat,inbothwesternblotandimmunohistochemistryapplicationsincludingformalinfixed,paraffinembeddedtissues.Seeapplicationsdetailforspecificuseinstructions.
BatchNo.seeviallabel
Unitsize100µg
AntigenAsyntheticpeptidecorrespondingtoasequenceattheC-terminusofhumanCD44cytoplasmicdomainaa728-742.Theimmunogendiffersbyonlysingleaminoacidbetweenhuman,mouseandratproteins.
SequenceDETRNLQNVDMKIGV
AntigenLocationcytoplasmic,C-terminus
AntigenLength15aa
AntibodyTypepolyclonal
IsotypeIgG
OtherNamesCDw44,Epican,ExtracellularmatrixreceptorIII,ECMR-III,GP90lymphocytehoming/adhesionreceptor,HUTCH-I,Heparansulfateproteoglycan,Hermesantigen,Hyaluronatereceptor,Phagocyticglycoprotein1,PGP-1,PhagocyticglycoproteinI,PGP-I,CD_antigen:CD44
AccessionP16070
ProducedinRabbit
MolecularWeightVariabledependinguponsplicing,80-to250-kDa
PurityAffinitypurifiedoverpeptide
ApplicationsWB:Westernblot:reducedRIPAsamplesormembranepreparations(0.1-.5ug/mL)dependentuponantigenloadandantibodyincubationtimesanddetectionsubstrateused.

IH:frozenoracetonefixedtissue:0.5-1.0ug.mL,permeABIlizationisnecessaryasepitopeisinternal
IH(P):1-2ug/mLwithHEIRtreatmentrequired.
Formlyophilized.
AppearanceEachvialcontains100ugpurifiedantibody,and5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3.
Reconstitution0.2mlofdistilledwaterwillyieldaconcentrationof500μg/ml.
StorageAt-20˚Cforoneyear.Afterreconstitution,at4˚Cforonemonth.Itcanalsobedividedintoaliquotsandstoredfrozenat-80˚Cforalongertime.Avoidrepeatedfreezingandthawing.
ExpiryDate12monthsafterpurchase.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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