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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit polyclonal antibody to human C-X-C Chemokine receptor 4 (18-33): Affinity purified/R-1143-100/100 µg
商品详细Biosensis/Rabbit polyclonal antibody to human C-X-C Chemokine receptor 4 (18-33): Affinity purified/R-1143-100/100 µg
Biosensis/Rabbit polyclonal antibody to human C-X-C Chemokine receptor 4 (18-33): Affinity purified/R-1143-100/100 µg
Biosensis/Rabbit polyclonal antibody to human C-X-C Chemokine receptor 4 (18-33): Affinity purified/R-1143-100/100 µg
商品编号: R-1143-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionTheC-X-CChemokinereceptor4(CXCR4)isamulti-passmembraneproteinthatbelongstotheG-proteincoupledreceptor1family.CXCR4isaspecificreceptorforstromalcell-derivedfactor-1(SDF-1)andiswidelyexpressedintissuesincludingperipheralbloodleukocytes,spleen,thymus,spinalcord,heart,placenta,lung,liver,skeletalmuscle,kidney,pancreas,cerebellum,cerebralcortexandmedulla.Atleast2isoformsareproducedbyalternativesplicing.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenAsyntheticpeptide(SGDYDSMKEPCFREEN)correspondingtoaregion(18-33)fromhumanC-X-CChemokinereceptor4.Toenhancetheimmunologicalresponse,thispeptidewascoupledtocarrierproteinBSA.
OtherNamesC-X-Cchemokinereceptortype4;CXC-R4;CXCR-4;Stromalcell-derivedfactor1receptor;SDF-1receptor;Fusin;Leukocyte-derivedseventransmembranedomainreceptor;LESTR;LCR1;FB22;NPYRL;HM89;CD184;CXCR4;
AccessionP61073CXCR4_HUMAN;
ProducedinRabbit
PurityAffinitypurifiedonantigencolumn
ApplicationsImmunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof0.1-0.5µg/mlisrecommendedforWB.HumanCXCR4(isoform1)hasapredictedlengthof352residuesandMWof40kDa.Aconcentrationof0.5-1.0µg/mlisrecommendedtodetecttheproteininhumanformalinfixedandparaffinembeddedtissues.Heatmediatedantigenretrieval(Boilingtheparaffinsectionsin10mMcitratebuffer,pH6.0,for20mins)isrequired.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen.
Cross-reactivityHuman(WB,IHC);rat(WB);predictedtoreactwithmouseduetosequencehomology;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3
ReconstitutionReconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°Cforuptosixmonths.Avoidfreeze-thawcycles
ExpiryDate12monthsafterpurchase(lyophilized)
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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