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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/兔抗NeuN/Fox3(1-99)多克隆抗体:全血清/R-3770-100/100µl
商品详细Biosensis/兔抗NeuN/Fox3(1-99)多克隆抗体:全血清/R-3770-100/100µl
Biosensis/兔抗NeuN/Fox3(1-99)多克隆抗体:全血清/R-3770-100/100µl
Biosensis/兔抗NeuN/Fox3(1-99)多克隆抗体:全血清/R-3770-100/100µl
商品编号: R-3770-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionFox3isoneofafamilyofmammalianhomologuesofFox-1.TheFoxproteinsareabout46kDainsize,andeachincludesacentralhighlyconservedRRMtypeRNArecognitionmotif.MuchinteresthasfocusedonFox3asaresultoftherecentfindingthatthisproteincorrespondstoNeuN,aneuronalnuclearantigen.NeuN/Fox-3hasafunctioninRNAsplicingandisexpressedheavilyandspecificallyinneuronalnucleiandcytoplasm.OurantibodywasraisedagainsttheN-terminal100aminoacidsofhumanFox3asexpressedinandpurifiedfromE.coli.WedidnotusefulllengthFox3asimmunogensincethethreemammalianFoxhomologues,namelyFox1,Fox2andFox3,includevirtuallyidenticalRRMmotifs.TheN-terminalregionofthethreemoleculesaremuchmorevariableinthethreemoleculessoantibodiesspecificforeachofthethreemoleculescanthereforebegenerated.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAntibodywasraisedagainsttheN-terminal100aminoacidsofhumanFox3asexpressedinandpurifiedfromE.coli.
AntigenLocation1-99
AntigenLength100aminoacids
AntibodyTypeAntiserum
OtherNamesFeminizinglocusonX;Fox-1;Fox3;NeuN;
AccessionA6NFN3FOX1C_HUMAN;
ProducedinRabbit
ApplicationsWesternBlotting(WB)andImmunocytochemistry(IC).Adilutionof1:5,000-1:10,000isrecommendedforWB.Adilutionof1:500-1:1,000isrecommendedforIC.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIC.Twoalternatetranscriptscanbeseenat46kDaand48kDainWB.Thisantibodyhasbeenusedsuccessfullyforimmunohistochemistryonparaformaldehydefixedratbraincortex(adult)tissue.Itdoesnotbindtothenucleiofperikaryaofnon-neuronalcellsmakingitagoodMarkertoidentifyneurons.
AntibodyAgainstNeuN/Fox3
Cross-reactivityRat.Predictedtoreactwithothermammalsduetosequencehomology.
BlastURLClickhere
FormLyophilised
AppearanceWhitepowder
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
SpecificReferencesHaoXZetal(2016)CombiningsystemicandstereotacticMEMRItodetectthecorrelationbetweengliosisandneuronalconnectivepathwayatthechronicstageafterstroke.JNeuroinflammation.13(1):156Species:Rat,ApplicationIH.

ZhouXFetal(2015)TranscriptionfactorsCOUP-TFIandCOUP-TFIIarerequiredfortheproductionofgranulecellsinthemouseolfactorybulb.Development.142(9):1593-605Species:Mouse,ApplicationIH.

SahaM,etal(2013)SpinalMitogen-ActivatedProteinKinasePhosphatase-3(MKP-3)isNecessaryfortheNormalResolutionofMechanicalAllodyniainaMouseModelofAcutePostoperativePain.J.Neurosci.33(43):17182-7

LiuXetal(2013)SuppressiveEffectofPhenolRedontheEpileptiformBurstActivityviaActivationofEstrogenReceptorsinPrimaryHippocampalCulture.PLoSONE8(4):e60189

LandryR.P.etal(2012)SpinalCannabinoidReceptorType2AgoNISTReducesMechanicalAllodyniaandInducesMitogen-ActivatedProteinKinasePhosphatasesinaRatModelofNeuropathicPain.JPain.2012Aug14

NdongC.etal(2012)Mitogenactivatedproteinkinasephosphatase-1preventsthedevelopmentoftactilesensitivityinarodentmodelofneuropathicpain.MolPain.2012Apr27;8(1):34.
GeneralReferencesKimK.K.etal(2009)Identificationofneuronalnuclei(NeuN)asFox-3,anewmemberoftheFox-1genefamilyofsplicingfactors.JBiolChem.2009Nov6;284(45):31052-61.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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