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当前位置: 首页 > 产品中心 > Functional_antibody > 针对人类酪氨酸激酶受体B型[4D3-F10]的Biosensis/小鼠单克隆抗体:IgG/M-853-100/100µg
商品详细针对人类酪氨酸激酶受体B型[4D3-F10]的Biosensis/小鼠单克隆抗体:IgG/M-853-100/100µg
针对人类酪氨酸激酶受体B型[4D3-F10]的Biosensis/小鼠单克隆抗体:IgG/M-853-100/100µg
针对人类酪氨酸激酶受体B型[4D3-F10]的Biosensis/小鼠单克隆抗体:IgG/M-853-100/100µg
商品编号: M-853-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
TyrosinekinasereceptortypeB(TrkB)isamemberoftheneurotrophictyrosinereceptorkinasefamily.Itisamembrane-boundreceptoranduponneurotrophinbinding,itphosphorylatesitselfaswellasMAPKpathwaysmembers.TrkBisthereceptorforbrain-derivedneurotrophicfactor(BDNF),neurotrophin-3andneurotrophin-4/5,butnotnervegrowthfactor(NGF).Itisinvolvedinthedevelopmentand/ormaintenanceofthenervoussystem.Itexistsinadynamicequilibriumbetweenmonomeric(lowaffinity)anddimeric(highaffinity)structures. Itisatran-membraneprotein.Thereare3namedisoformsproducedbyalternativesplicing.Additionalisoformsseemtoexist.Thedifferentformsaredifferentiallyexpressedinvariouscelltypesincludingneuronsandmicroglia.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenRecombinantproteinofhumanTyrosinekinasereceptortypeB(isoformTrkB-T1)withaGSTtag.
IsotypeIgG2a,kappa
Clone4D3-F10
OtherNamesTropomyosin-relatedkinasereceptor;BDNF/NT-3growthfactorsreceptor;Neurotrophictyrosinekinasereceptortype2;TrkBtyrosinekinase;GP145-TrkB;Trk-B;TrkB;NTRK2;TRKB
AccessionNTRK2_HUMAN
ProducedinMouse
PurityProteinGpurifiedimmunoglobulin
ApplicationsThisantibodyisrecommendedforWB,sandwichELISAandFlowCytometry.Use2ug/10^6cellsforFlowCytometry.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen.
Cross-reactivityHuman.Otherspecieshavenotbeentested.
BlastitToseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit.
FormLyophilisedfromPBSpH7.2
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforhigherstABIlityorat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchase
GeneralReferences1.MizoguchiYetal.,JImmunol.2009Dec15;183(12):7778-86.
2.Spencer-SegalJLetal.JNeurosci.2011May4;31(18):6780-90.
3.NakajimaKetal.Glia.1998Nov;24(3):272-89.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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