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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit polyclonal antibody to human APPL1 (455-709): Whole serum/R-1331-100/100 µl
商品详细Biosensis/Rabbit polyclonal antibody to human APPL1 (455-709): Whole serum/R-1331-100/100 µl
Biosensis/Rabbit polyclonal antibody to human APPL1 (455-709): Whole serum/R-1331-100/100 µl
Biosensis/Rabbit polyclonal antibody to human APPL1 (455-709): Whole serum/R-1331-100/100 µl
商品编号: R-1331-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description APPL1 (adaptor protein containing PH domain, PTB domain and leucine zipper motif 1) mediates adiponectin signaling in various types of cells. APPL1 is also thought to have a role in insulin signaling.
Batch No. See product label
Unit size 100 µl
Antigen The C-terminus of Human APPL1 protein (amino acids: 455-709) conjugated to GST.
Other Names DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1; APPL1; APPL; DIP13A; KIAA1428;
Accession Q9UKG1 DP13A_HUMAN;
Produced in Rabbit
Purity Whole serum
Applications Western Blotting (WB) and Immunoprecipitation (IP). A dilution of 1:1,000 is recommended for WB. A concentration of 3 µl/reaction is recommended for IP. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Cross-reactivity This antiserum is known to recognise both mouse and human APPL1.
Blast URL Click here
Form Lyophilised
Appearance White powder
Reconstitution Reconstitute in 100 µl of sterile distilled water. Centrifuge to remove any insoluble material.
Storage At least 12 months after purchase at 2 - 4°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
Expiry Date 12 months after purchase
References 1. Mao X. et al (2006) APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function Nat Cell Biol. 2006 May;8(5):516-23.
2. Wang C. et al (2009) Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells J Biol Chem. 2009 Nov 13;284(46):31608-15.
3. Zhou L. et al (2009) Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways J Biol Chem. 2009 Aug 14;284(33):22426-35
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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