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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Mouse monoclonal antibody to Protein S100-beta [SH-B1]: IgG/M-1746-100/100 µg
商品详细Biosensis/Mouse monoclonal antibody to Protein S100-beta [SH-B1]: IgG/M-1746-100/100 µg
Biosensis/Mouse monoclonal antibody to Protein S100-beta [SH-B1]: IgG/M-1746-100/100 µg
Biosensis/Mouse monoclonal antibody to Protein S100-beta [SH-B1]: IgG/M-1746-100/100 µg
商品编号: M-1746-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionProteinS100betabelongstotheS100familyofproteinscontaining2EF-handcalciumbindingmotifs.S100proteinsarelocalizedinthecytoplasmand/ornucleusofawiderangeofcells,andareinvolvedintheregulationofanumberofcellularprocessessuchascellcycleprogressionanddifferentiation.Amongbraincells,S100betaisoftenusedasaMarkerforastrocytes.The2subunitsofS100proteinaretheproductsofseparategenes.ThebetasubunitispresentinallS100positivecellsandtumourswhereasthealphasubunitisdetectableonlyinspecifictissuessuchasheart,skeletalmuscleandbrain.TheS100proteinisahomodimercomposedoftwoalphasubunits(S100a)ortwobetasubunits(S100b)orasaheterodimerwithonealphaandbetasubunit(S100aborS100ao).Thisantibodyreactsspecificallywiththebetasubunit.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenBovinebrainS-100b
AntibodyTypeMousemonoclonal
CloneSH-B1
OtherNamesS100B;CalciumbindingproteinB1;
AccessionP02638S100B_BOVIN
ProducedinMouse
MolecularWeightThepredictedlengthofbovineS100betasubunitis92residuesandtheMWofthemonomeris11kDa.
PurityAscites
ApplicationsImmunohistochemistry(IHC).Aconcentrationof1.0-2.0µg/mLisrecommendedtodetectS100betasubunitinparaffinembeddedtissues.Antigenretrievalbyheatisrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyIHCagainsttheantigen.
SpeciesAgainstBovine
Cross-reactivityHuman,rabbitandrat.Maycross-reactwithhorseandmonkeyS100-betabasedonaminoacidsequencesimilarities.
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilizedfrommouseascitesfluidcontaining1.2%sodiumacetate,2mgBSA,with0.01mgNaN3aspreservative.
ReconstitutionReconstitutein1mLofPBSbuffertoachieveanantibodyconcentrationof100µg/mL.Centrifugetoremoveanyinsolublematerial.
Storage12monthsafterpurchaseat-20°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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