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Biosensis/Mouse monoclonal antibody to rh BDNF [3C11]: IgG/M-1736-100/100 µg. Supplied as 2 x 50 µg vials.
![Biosensis/Mouse monoclonal antibody to rh BDNF [3C11]: IgG/M-1736-100/100 µg. Supplied as 2 x 50 µg vials.](https://www.ebiomall.cn/images/biosensis/201712/M-1736-100_WB.jpg)
Biosensis/Mouse monoclonal antibody to rh BDNF [3C11]: IgG/M-1736-100/100 µg. Supplied as 2 x 50 µg vials.
商品编号：
M-1736-100
品牌：
Biosensis inc
市场价：
¥7340.00
美元价：
4404.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family. |
| Related products | Available as 50 µg. |
| Batch No. | See product label. |
| Unit size | 100 µg. Supplied as 2 x 50 µg vials. |
| Antigen | Recombinant human mature BDNF expressed in E.coli |
| Antibody Type | Mouse monoclonal. |
| Clone | 3C11 |
| Other Names | Brain-derived neurotrophic factor; Abrineurin; proBDNF |
| Accession | BDNF_HUMAN |
| Produced in | Mouse |
| Molecular Weight | Mature BDNF dimer has a molecular weight of 28 kDa. In Western Blotting, mature BDNF monomer migrates at 14 kDa. |
| Purity | Protein G purified mouse IgG. |
| Applications | ELISA (50-100 ng/mL), WB (0.2 to 2 µg/mL), IF (2 to 20 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity | Detects human, mouse, rat, guinea pig BDNF. Expected to detect BDNF from other species due to sequence homology. |
| Blast URL | Click here |
| Form | Lyophilized from a solution containing PBS pH 7.4, 3% trehalose, with 0.1% sodium azide. |
| Reconstitution | Spin vial briefly before opening. Reconstitute each vial with 50 µL sterile water to obtain a concentration of 1 mg/mL. |
| Storage | Store lyophilized antibody at -20°C to -80°C protected from moisture. After reconstitution divide antibody into useful aliquots and keep aliquots at -20°C to -80°C for a higher stability. Working aliquots can be kept at 2-8°C for up to 1 month. Avoid repetitive freeze/thaw cycles. |
| Expiry Date | 12 months after purchase if unopened. |
| General References | Chacon-Fernandez P et al. (2016), Brain-derived Neurotrophic Factor in Megakaryocytes. J Biol Chem. 2016 May 6; 291(19): 98729881. Species: Human. Application: WB, IF. |
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司，致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验，并在生命科学研究和诊断市场的生命科学抗体，试剂和试剂盒的商业化方面拥有50多年的经验。
品牌分类
TR-200-BG型
PE-1243-50型
抗体试剂盒
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神经营养因子
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细胞内贩运
电话：PE-1239-5
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2个平板ELISA试剂盒
M-1763-100英尺
TR-200-BGT公司
电话：PE-1239-2
PE-1242-5型
M-1249-100号
神经营养因子受体
细胞周期调节器
S-1759-100号
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PE-019-100型
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PE-003-100
1个平板ELISA试剂盒
BL-003-1000型
PE-1246-2型
感觉神经系统
PE-1253-100型
TR-100-FJ
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神经内分泌
M-1728-100型
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PE-1608-1型
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PE-1243-25
细胞标记
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自噬
PE-1242-2型
其他神经元
神经递质和酶
抗氧化酶
神经元标志物
标记抗体
BL-004-500型
PE-019-25
PE-1608-10型
BL-002-1250型
受体体嵌合体
信令与转录
基质和粘附分子
BL-001-1250型
癌症
PE-019-500
干细胞
连接蛋白
TR-300-AG型
细胞凋亡
PE-1252-100型
生长因子
发展
阿尔茨海默氏症/帕金森氏症
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