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当前位置: 首页 > 产品中心 > Polyclonal_antibody > Biosensis/兔对小鼠白细胞介素1β(IL-1β)亲和纯化的多克隆/R-1658-100/100μg
商品详细Biosensis/兔对小鼠白细胞介素1β(IL-1β)亲和纯化的多克隆/R-1658-100/100μg
Biosensis/兔对小鼠白细胞介素1β(IL-1β)亲和纯化的多克隆/R-1658-100/100μg
Biosensis/兔对小鼠白细胞介素1β(IL-1β)亲和纯化的多克隆/R-1658-100/100μg
商品编号: R-1658-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 多克隆抗体
公司分类: Polyclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionInterleukin-1beta(IL-1β)alsoknowascatabolin,isacytokineproteinthatinhumansisencodedbytheIL1Bgene,whichlocalizestothelongarmofchromosome2.Interleukin1wasdiscoveredbyGeryin1972.Henameditlymphocyte-activatingfactor(LAF)becauseitwasalymphocytemitogen.Itwasnotuntil1985thatinterleukin1wasdiscoveredtoconsistoftwodistinctproteins,nowcalledinterleukin-1alphaandinterleukin-1beta.IL-1βisamemberoftheinterleukin1cytokinefamily.Thiscytokineisproducedbyactivatedmacrophagesasaproprotein,whichisproteolyticallyprocessedtoitsactiveformbycaspase1(CASP1/ICE).Thiscytokineisanimportantmediatoroftheinflammatoryresponse,andisinvolvedinavarietyofcellularactivities,includingcellproliferation,differentiation,andapoptosis.Theinductionofcyclooxygenase-2(PTGS2/COX2)bythiscytokineinthecentralnervoussystem(CNS)isfoundtocontributetoinflammatorypainhypersensitivity.Reference:http://en.wikipedia.org/wiki/IL1B
BiosensisrabbitpolyclonaltomouseIL-1βhasbeentestedagainstmousetissuelysatesandreactswellinwesternblots.Otherapplicationsandotherspecieshavenotyetbeentested.
BatchNo.seeviallabel
Unitsize100ug
AntigenAminoacids250-265aa,(FLGNNSGQDIIDFTME)frommouseIL-betaprotein
SequenceFLGNNSGQDIIDFTME
AntigenLocationC-terminus
AntigenLength15aminoacids
AntibodyTypeRabbitIgG
IsotypeIgG
AccessionP10749Here
ProducedinRabbit
CompoundNameInterleukin1beta,IL-1beta
Purity100ugofaffinitypurifiedrabbitIgGin5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3buffer.
ApplicationsWesternblot0.5-1.0ug/mL;detectsabandat~17kDaforthematuremouseform.Insomeinstancestheproformat~30kDacanalsobedetected.Thisantibodydoesnotfunctionforimmunohistochemistry.
SpecificityMouse,otherspeciesnotyettested.Theantibodymayalsoreactwithratduetosequencehomology.
SpeciesAgainstMouse
AntibodyAgainstMouse
Cross-reactivityOtherspeciesnotyettested
Formaffinitypurified
Appearancelyophilized
ReconstitutionReconstitutewith200uLofdistilledwater,finalconcentration0.5mg/mL
StorageAt2-8degCforoneyear(lyophilized).Afterreconstitutionaliquotandstorefrozenat-20degCforuptosixmonths.Avoidrepeatedfreezingandthawing.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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