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Biosensis/Rabbit antibody to AP-1 complex subunit beta-1 (11-29): whole serum/R-167-100/100 µl
Biosensis/Rabbit antibody to AP-1 complex subunit beta-1 (11-29): whole serum/R-167-100/100 µl
商品编号:
R-167-100
品牌:
Biosensis inc
市场价:
¥5940.00
美元价:
3564.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | FUNCTION:Subunitofclathrin-associatedadaptorproteincomplex1thatplaysaroleinproteinsortinginthelate-Golgi/trans-Golginetwork(TGN)and/orendosomes.TheAPcomplexesmediateboththerecruitmentofclathrintomembranesandtherecognitionofsortingsignalswithinthecytosolictailsoftransmembranecargomolecules.SUBUNIT:Adaptorproteincomplex1(AP-1)isanheterotetramercomposedoftwolargeadaptins(gamma1/AP1G1orgamma2/AP1G2andbeta1A/AP1B1orbeta1B/AP1B1),amediumadaptin(mu1A/AP1M1ormu1B/AP1M2)andasmalladaptin(sigma1A/AP1S1orsigma1B/AP1S2orsigma1C/AP1S3).SUBCELLULARLOCATION:Golgiapparatus.Cytoplasmicvesicle;cytoplasmicvesiclemembrane;peripheralmembraneprotein;cytoplasmicside.Note=ComponentofthecoatsurroundingthecytoplasmicfaceofcoatedvesicleslocatedattheGolgicomplex.ALTERNATIVEPRODUCTS:2namedisoformsproducedbyalternativesplicing.TISSUESPECIFICITY:Widelyexpressed.DISEASE:DeletionoftheAP1B1genemayplayaroleinthetumOrigenesisofmeningiomas.SIMILARITY:Belongstotheadaptorcomplexeslargesubunitfamily. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | Asyntheticpeptide(C-KKGEIFELKAELNSDKKEK)correspondingtotheaminoacids11-29ofhumanAP-1complexsubunitbeta-1conjugatedtodiphtheriatoxinhasbeenusedastheimmunogen.ThepeptideishomologouswiththecorrespondingsequencederivedfromAP-1complexsubunitbeta-1proteininmouse,ratandbovine. |
OtherNames | Adapter-relatedproteincomplex1beta-1subunit;Beta-adaptin1;AdaptorproteincomplexAP-1beta-1subunit;GolgiadaptorHA1/AP1adaptinbetasubunit;Clathrinassemblyproteincomplex1betalargechain;AP1B1;ADTB1;BAM22 |
Accession | AP1B1_HUMAN AP1B1_MOUSE AP1B1_RAT AP1B1_BOVIN |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC,WB.Thisantibodyworkssuperblyinimmunohistochemistryonfrozenorparaffinembeddedtissues.Antigenretrievalhasbeenusedintestingbutmaynotbenecessary.Typicalworkingdilutionsforroutineimmunohistochemistryare1:1000to1:5000dependingontissueanddetectionmethod.Forwesternblottingadilutionrangeof1:100to1:10000isrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ThisantibodyhasbeenshowntobespecificforAP-1complexsubunitbeta-1. |
Cross-reactivity | Ratandhuman,otherspecieshavenotyettested. |
Blastit | Ifyouwouldliketousethisproductinanotherspeicesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeciesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles.Glycerol(1:1)maybeaddedforanadditionalstability. |
ExpiryDate | 12monthsafterpurchase |
References | 1.PeyrardM,etal.Genomics36:112-117(1996). 2.PeyrardM,etal.Hum.Mol.Genet.3:1393-1399(1994). 3.SackstederC.A,etal.Biochemistry45:8009-8022(2006). 4.GuilbaudC,etal.Mamm.Genome8:651-656(1997). 5.KirchhausenT,etal.Proc.Natl.Acad.Sci.U.S.A.86:2612-2616(1989). |
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
品牌分类
TR-200-BG型
PE-1243-50型
抗体试剂盒
PE-1246-5型
TR-100-BG型
S-1754-500型
神经营养因子
糖尿病与肥胖
细胞内贩运
电话:PE-1239-5
神经肽和受体
B-100-PS型
受体和通道分子
2个平板ELISA试剂盒
M-1763-100英尺
TR-200-BGT公司
电话:PE-1239-2
PE-1242-5型
M-1249-100号
神经营养因子受体
细胞周期调节器
S-1759-100号
PE-1606-100型
PE-1762-100型
B-200-PS型
PE-019-100型
PE-1241-5型
PE-003-100
1个平板ELISA试剂盒
BL-003-1000型
PE-1246-2型
感觉神经系统
PE-1253-100型
TR-100-FJ
BL-005-500型
神经内分泌
M-1728-100型
DNA损伤与修复
PE-001-100型
PE-1608-1型
TR-400-AG公司
PE-1243-25
细胞标记
PE-1608-5型
TR-100-FJT
自噬
PE-1242-2型
其他神经元
神经递质和酶
抗氧化酶
神经元标志物
标记抗体
BL-004-500型
PE-019-25
PE-1608-10型
BL-002-1250型
受体体嵌合体
信令与转录
基质和粘附分子
BL-001-1250型
癌症
PE-019-500
干细胞
连接蛋白
TR-300-AG型
细胞凋亡
PE-1252-100型
生长因子
发展
阿尔茨海默氏症/帕金森氏症
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