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当前位置: 首页 > 产品中心 > Functional_antibody > 生物传感器/兔抗网格蛋白抗体(619-638):全血清/R-165-100/100µl
商品详细生物传感器/兔抗网格蛋白抗体(619-638):全血清/R-165-100/100µl
生物传感器/兔抗网格蛋白抗体(619-638):全血清/R-165-100/100µl
生物传感器/兔抗网格蛋白抗体(619-638):全血清/R-165-100/100µl
商品编号: R-165-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionClathrinisamajorproteincomponentofthepolyhedralcoatofcoatedpitsandvesicles.Twodifferentadapterproteincomplexeslinktheclathrinlatticetoeithertheplasmamembraneorthetrans-Golginetwork.Thesespecialisedorganellesareinvolvedintheintracellulartraffickingofreceptorsandendocytosisofavarietyofmacromolecules.Clathrintriskelions,composedof3heavychainsand3lightchains,arethebasicsubunitsoftheclathrincoat.Inthepresenceoflightchains,hubassemblyisinfluencedbyboththepHandtheconcentrationofcalcium.Clathrinlocalisestothecytoplasmicfaceofcoatedpitandvesiclemembranes.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(KAGLLQRALEHFTDLYDIKR)correspondingtotheaminoacids619-638ofratclathrinconjugatedtodiphtheriatoxinhasbeenusedastheimmunogen.Thepeptideishomologouswiththecorrespondingsequencederivedfromclathrinproteininmouse,humanandbovine.
OtherNamesClathrinheavychain;Clathrinheavychain1;CLH-17;CLTC
AccessionCLH_RAT
ProducedinRabbit
PurityWholeserum
ApplicationsIHC,WB.Thisantibodyworksinimmunohistochemistryonfrozenorparaffinembeddedtissues.Antigenretrievalhasbeenusedintestingbutmaynotbenecessary.Typicalworkingdilutionsforroutineimmunohistochemistryare1:100to1:4000dependingontissueanddetectionmethod.Itisusualtouseapproximatelya10-foldincreaseforconfocalmicroscopyi.e.adilutionrangeof1:100to1:400.Forwesternblottingadilutionrangeof1:1000to1:8000isrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThisantibodyhasbeenshowntobespecificforclathrin.
Cross-reactivityRat
BlastitIfyouwouldliketousethisproductinanotherspeicesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20°CforahigherstABIlity,andat4°Cwithanappropriateantibacterialagent.
References1.KirchhausenT,etal.Proc.Natl.Acad.Sci.U.S.A.84:8805-8809(1987).
2.TerHaarE,etal.Cell95:563-573(1998).
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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