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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit antibody to Nociceptin (139-151): whole serum/R-105-100/100 µl
商品详细Biosensis/Rabbit antibody to Nociceptin (139-151): whole serum/R-105-100/100 µl
Biosensis/Rabbit antibody to Nociceptin (139-151): whole serum/R-105-100/100 µl
Biosensis/Rabbit antibody to Nociceptin (139-151): whole serum/R-105-100/100 µl
商品编号: R-105-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionFUNCTION:Nociceptinistheligandoftheopioidreceptor-likereceptor(OPRL1).Itmayactasatransmitterinthebrainbymodulatingnociceptiveandlocomotorbehavior.Maybeinvolvedinneuronaldifferentiationanddevelopment.SUBCELLULARLOCATION:Secretedprotein.TISSUESPECIFICITY:Expressedpredominantlyinthespinalcordandbrain,beingmoreabundantinthehypothalamusandstriatum.Alsofoundinsmallamountsinovary.PTM:Specificenzymaticcleavagesatpairedbasicresiduesprobablyyieldotheractivepeptidesbesidesnociceptin.PTM:TheN-terminaldomaincontains6conservedcysteinesthoughttobeinvolvedindisulfidebondingand/orprocessing.SIMILARITY:Belongstotheopioidneuropeptideprecursorfamily.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(C-TGARKSARKLANQ)aspartofratNociceptinpeptide(aa:139-151)conjugatedtodiphtheriatoxoid
OtherNamesTherearenosynonymsforthispeptide;howevertheprecursorproteincontains:Neuropeptide1;Nociceptin(OrphaninFQ;PPNOC;ORL1receptoragoNIST);Neuropeptide2
AccessionPNOC_RAT
ProducedinRabbit
PurityWholeserum
ApplicationsIHC,1-siteELISA.Adilutionof1:1000to1:3000isrecommendedforbothapplications.Thisantibodymayalsobeusedforstainingofnervefibresinguineapigmyentericplexus.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificityhasbeentestedbytheuseofdifferentpeptidesincludingenkephalin,dynorphinandendorphinforabsorptioninimmunihistochemistry.
Cross-reactivityThisantibodyisknowntocrossreactwithguineapigandrat.
BlastitIfyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20°CforahigherstABIlity,andat4°Cwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
ReferencesDarlandetal.(1998)TrendsNeurosci.21:215-221
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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