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当前位置: 首页 > 产品中心 > Functional_antibody > 生物传感器/兔抗ChAT抗体(167-188):亲和纯化/R-1621-100/100µg
商品详细生物传感器/兔抗ChAT抗体(167-188):亲和纯化/R-1621-100/100µg
生物传感器/兔抗ChAT抗体(167-188):亲和纯化/R-1621-100/100µg
生物传感器/兔抗ChAT抗体(167-188):亲和纯化/R-1621-100/100µg
商品编号: R-1621-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
Related products PE-1762-100, ChAT control peptide (167-188)
Unit size 100 µg
Antigen A synthetic peptide (GLFSSYRLPGHTQDTLVAQKSS) as a part of porcine ChAT protein (aa: 167-188) conjugated to KLH
Other Names Choline O-acetyltransferase, CHOACTase, Choline acetylase
Accession CLAT_PIG
Produced in NZ white rabbit
Purity Affinity purified
Applications IHC, 1 site ELISA. Use at a concentration of 1 µg/ml. This antiserum will superbly stain both cell bodies and nerve terminal. The optimal dilution should be determined by the end user.
Specificity This antibody stains cholinergic neurons in human, rat, guinea-pig and rabbit central and peripheral nervous systems.
Cross-reactivity This antiserum is known to react with ChAT of origin: human, rat, guinea-pig and rabbit.
Blast it If you would like to use this product in another species other than those specified here, or to see the shared identity between the immunogen used here in different speices and/or other molecules, simply copy the immunogen (from the Immunogen field) and paste it HERE and blast/format it. Note that, antisera raised against synthetic peptides are quite often very specific for that peptide ie, only one single amino acid difference may be enough to restrict the specificity to a particular molecule. Regardless, you can always contact us if you need assistance with this.
Form Lyophilised
Reconstitution Reconstitute in 100µl of sterile water. Centrifuge to remove any insoluble material.
Storage After reconstitution keep aliquots at -20°C for a higher stability, and at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Specific References Leong WK, Klaric TS, Lin Y, Lewis MD, Koblar SA.(2013) Upregulation of the neuronal Per-Arnt-Sim domain protein 4 (Npas4) in the rat corticolimbic system following focal cerebral ischemia. Eur J Neurosci. 2013 Feb 22. doi: 10.1111/ejn.12163. [Epub ahead of print] Application: IH; species Rat PubMed ID
References Benecke et al. (1993). J. Neurochemistry. 61: 804-811
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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