4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit antibody to ChAT (167-188): whole serum/R-043-100/100 µl
商品详细Biosensis/Rabbit antibody to ChAT (167-188): whole serum/R-043-100/100 µl
Biosensis/Rabbit antibody to ChAT (167-188): whole serum/R-043-100/100 µl
Biosensis/Rabbit antibody to ChAT (167-188): whole serum/R-043-100/100 µl
商品编号: R-043-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionThisgeneencodesanenzymewhichcatalyzesthebiosynthesisoftheneurotransmitteracetylcholine.Thisgeneproductisacharacteristicfeatureofcholinergicneurons,andchangesintheseneuronsmayexplainsomeofthesymptomsofAlzheimer"sdisease.PolymorphismsinthisgenehavebeenassociatedwithAlzheimer"sdiseaseandmildcognitiveimpairment.Mutationsinthisgeneareassociatedwithcongenitalmyasthenicsyndromeassociatedwithepisodicapnea.Multipletranscriptvariantsencodingdifferentisoformshavebeenfoundforthisgene,andsomeofthesevariantshavebeenshowntoencodemorethanoneisoform.[providedbyRefSeq,May2010]
RelatedproductsPE-1762-100,ChATcontrolpeptide(167-188)
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(GLFSSYRLPGHTQDTLVAQKSS)asapartofporcineChATprotein(aa:167-188)conjugatedtoKLH
OtherNamesCholineO-acetyltransferase;CHOACTase;Cholineacetylase
AccessionCLAT_PIG
ProducedinRabbit
PurityWholeserum
ApplicationsImmunohistochemistry/cytochemistryon4%PFAorformalinfixedfrozensections;paraffinsectionscanbemoredifficultandrequiremoreextensiveantigenrecoverymethods.1:400-1:2000dependingupdetectionandincubationtimes
ELISA:directantigenELISA
Thisantiserumwillsuperblystainbothcellbodiesandnerveterminal,andworksparticularlywellinentericandperipheralneurons.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThisantiserumstainscholinergicneuronsinguinea-pigandrabbit.
Cross-reactivityThisantiserumisknowntoreactwithChAToforiginguinea-pig,mouse,ratandrabbit.
BlastitIfyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20°CforahigherstABIlity,andat4°Cwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
SpecificReferencesBeigMI,DampneyBWandCarriveP(2014)Bothox1randox2rorexinreceptorscontributetothecardiovascularandlocomotorcomponentsofthenoveltystressresponseintherat.NeuropharmacologySeptember16[Epubaheadofprint]Application:IH;Species:Rat

EllisKM,O"CarrollDC,LewisMD,RychkovGY,KoblarSA(2014)Neurogenicpotentialofdentalpulpstemcellsisolatedfrommurineincisors.StemCellResTher.2014Feb27;5(1):30.Application:IF;Species:Mouse

LeongWK,KlaricTS,LinY,LewisMD,KoblarSA(2013)UpregulationoftheneuronalPer-Arnt-Simdomainprotein4(Npas4)intheratcorticolimbicsystemfollowingfocalcerebralischemia.EurJNeurosci.2013Jun;37(11):1875-84Application:IH;Species:Rat

LiSetal(2011)TheexpressionandlocalizationofPrune2mRNAinthecentralnervoussystem.NeurosciLett.Oct10;503(3):208-14.
GeneralReferencesBeneckeetal.(1993).J.NeuRochemistry.61:804-811
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
联络我们
服务热线:4000-520-616
(限工作日9:00-18:00)
QQ :1570468124
手机:18915418616