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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Rabbit antibody to native DBH: whole serum/R-108-100/100 µl
商品详细Biosensis/Rabbit antibody to native DBH: whole serum/R-108-100/100 µl
Biosensis/Rabbit antibody to native DBH: whole serum/R-108-100/100 µl
Biosensis/Rabbit antibody to native DBH: whole serum/R-108-100/100 µl
商品编号: R-108-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionDBHisanoxireductasebelongingtothecoppertypeIIascorbate-dependentmonooxygenasefamily.DBHexistsasahomotetramercomposedoftwonon-covalentlybounddisulfide-linkeddimers.Itispresentinthesynapticvesiclesofpostganglionicsympatheticneuronsandconvertsdopaminetonorepinephrine.Itbinds2copperionsand1PQQpersubunit.Dependingonthepresenceofasignalpeptide,DBHcanexistinbothsolubleandmembrane-boundforms.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenNativeenzymepreparedfromBovineadrenalglands.Puritywasgreaterthan95%byPAGE.
OtherNamesDopaminebeta-hydroxylase;Dopaminebeta-monooxygenase;Solubledopaminebeta-hydroxylase;
AccessionP15101DOPO_BOVIN;
ProducedinRabbit
PurityWholeserum
ApplicationsIHC(frozen),WesternBlot,rADIoimmunoassayandinhibitionofenzymaticactivity.Recommendedtobeusedatadilutionof1:500to1:2000.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThisantiserumhasbeenextensivelycharacterisedinseverallaboratories.ItreactswithasinglebandonwesternblotofbovineadrenalhomogenatesandstainsonlycellsknowntocontainDBH,suchassympatheticneurons,adrenalmedullarycellsandcentraladrenergicneurons.Stainingisabolishedbypreincubationwiththeenzyme.
Cross-reactivityThisantibodyisknowntoreactwithbovine,human,guineapigandratDBH.
BlastitIfyouwouldliketoseethesharedidentitybetweendifferentspeciesorotherproteinsfollowthelinkinAccessionfield,selectthenthesequence(makesurethatyouareselectingthesequencethatyouareinterestedin,asthesequencemaybetheprecursorratherthanthematureproteinforexample)andcopyandpasteitHEREandblast/formatit.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20°CforahigherstABIlity,andat4°Cwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles.Glycerol(1:1)maybeaddedforanadditionalstability.
SpecificReferencesBowolaksonoA.(2012)MolecularRegulationofNoradrenalineinBovineCorpusLuteum.HAYATIJournalofBiosciencesJune2012Vol.19No.2,p81-87
Blanco-CenturionC.etal(2004)Effectsofhypocretin2-saporinandantidopamine-beta-hydroxylase-saporinneurotoxiclesionsofthedorsolateralponsonsleepandmuscletone.EurJNeurosci.2004May;19(10):2741-52.
OhshitaN.etal(2004)Characteristicsofthetrigeminaldepressorresponseincats.JNeurosciRes.2004Jun15;76(6):891-901.
References1.RushR.A.etal(1980)GutRevclinLabSci12:241
2.VerndellI.M.etal(1982)JHistochemCytochem30:682
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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