生物传感器/抗GFRα-2（376-390）的兔抗体：全血清/R-067-100/100µl
商品编号：
R-067-100
品牌：
Biosensis inc
市场价：
¥5940.00
美元价：
3564.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | FUNCTION: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. SUBCELLULAR LOCATION: Cell membrane; lipid-anchor; GPI-anchor (By similarity). ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. |
| Batch No. | See product label |
| Unit size | 100 µl |
| Antigen | A synthetic peptide (PRVEKTPSLPDDLSD) as a part of human GFR alpha-2 protein (aa: 376-390) conjugated to KLH. |
| Sequence | PRVEKTPSLPDDLSD |
| Antigen Location | 376-390 |
| Other Names | GDNF family receptor alpha-2; GFR-alpha-2; Neurturin receptor alpha; NTNR-alpha; NRTNR-alpha; TGF-beta-related neurotrophic factor receptor 2; GDNF receptor beta; GDNFR-beta; RET ligand 2 |
| Accession | GFRA2_HUMAN |
| Produced in | Rabbit |
| Purity | Whole serum |
| Applications | IHC, WB. A dilution of 1:500 to 1:1000 is recommended for both applications. This antibody stains beautifully the large neurons in the rat DRG. This antibody also is ideal for WB analysis of rat DRG and brain homogenate. The optimal dilution should be determined by the end user, but a dilution of 1 in 500 is recommended for initial testing. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity | Western blot analysis indicates a high level of specificity to GFR alpha-2 for this antiserum. |
| Cross-reactivity | This antibody is known to react with rat GFR alpha-2 and from IHC analysis, there appears to be no cross-reactivity with other members of the GFR family. |
| Blast it | If you would like to use this product in another species other than those specified here, or to see the shared ID between the immunogen used here in different speices and/or other molecules, simply copy the immunogen (from the Immunogen field) and paste it HERE and blast/format it. Note that, antisera raised against synthetic peptides are quite often very specific for that peptide ie, only one single amino acid difference may be enough to restrict the specificity to a particular molecule. Regardless, you can always contact us if you need assistance with this. |
| Form | Lyophilised |
| Reconstitution | Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage | After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles. |
| References | Rossi et al. (1999) Neuron. 22(2): 243
Klein et al. (1997) Nature. 387(6634): 717 |
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司，致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验，并在生命科学研究和诊断市场的生命科学抗体，试剂和试剂盒的商业化方面拥有50多年的经验。
品牌分类
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PE-1243-50型
抗体试剂盒
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M-1249-100号
神经营养因子受体
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自噬
PE-1242-2型
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BL-004-500型
PE-019-25
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BL-001-1250型
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PE-019-500
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发展
阿尔茨海默氏症/帕金森氏症
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