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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/抗酪氨酸激酶受体C(TrkC)的兔抗体:全血清/R-151-100/100µl
商品详细Biosensis/抗酪氨酸激酶受体C(TrkC)的兔抗体:全血清/R-151-100/100µl
Biosensis/抗酪氨酸激酶受体C(TrkC)的兔抗体:全血清/R-151-100/100µl
Biosensis/抗酪氨酸激酶受体C(TrkC)的兔抗体:全血清/R-151-100/100µl
商品编号: R-151-100
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionTrkCisamemberoftheneurotrophictyrosinereceptorkinasefamily.TrkCisamembrane-boundreceptorthatuponneurotrophinbinding,phosphorylatesitselfandmembersoftheMAPKpathway.TrkCisthereceptorforneurotrophin-3(NT-3). SignallingthroughTrkCleadstocelldifferentiationandmayplayaroleinthedevelopmentofproprioceptiveneuronsthatsensebodyposition.SUBUNIT:Existsinadynamicequilibriumbetweenmonomeric(lowaffinity)anddimeric(highaffinity)structures.SUBCELLULARLOCATION:Membrane;single-passtypeImembraneprotein.ALTERNATIVEPRODUCTS:4namedisoformsproducedbyalternativesplicing.Additionalisoformsseemtoexist.MutationsinTrkChavebeenassociatedwithmedulloblastomas,secretorybreastcarcinomasandothercancers.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenExtracellulardomainofglycosylatedhumanTrkCproteinproducedinCHOcellswasusedastheimmunogen.
OtherNamesTropomyosin-relatedkinasereceptor;NT-3growthfactorreceptor;Neurotrophictyrosinekinasereceptortype3;TrkCtyrosinekinase;GP145-TrkC;Trk-C;NTRK3;TRKC
AccessionNTRK3_HUMAN
ProducedinRabbit
PurityWholeserum
ApplicationsIHC.Adilutionof1:1000to1:3000isrecommendedforthisapplication.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificitywasdemonstratedbyimmunohistochemistry.Thisantibodywasusedtostaincryostatsectionsoftheratperipheralsensoryganglia.
Cross-reactivityReactswithhuman,ratandmouseTrkC.Otherspecieshavenotyetbeentested.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
ReferencesZhangFX,etal.(2005)BrainRes.1062(1-2)pp.92-100.
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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