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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Sheep antibody to rh NT3: IgG/S-057-500/500 µg
商品详细Biosensis/Sheep antibody to rh NT3: IgG/S-057-500/500 µg
Biosensis/Sheep antibody to rh NT3: IgG/S-057-500/500 µg
Biosensis/Sheep antibody to rh NT3: IgG/S-057-500/500 µg
商品编号: S-057-500
品牌: Biosensis inc
市场价: ¥5940.00
美元价: 3564.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionNT3isamemberoftheneurotrophinfamily,thatcontrolssurvivalanddifferentiationofvisceralandproprioceptivesensoryneurons.NT3iscloselyrelatedtobothNGFandBDNF.Itmaybeinvolvedinthemaintenanceoftheadultnervoussystem,andmayaffectdevelopmentofneuronsintheembryowhenitisexpressedinhumanplacenta.NT3-deficientmicegeneratedbygenetargetingdisplaysevveremovementdefectsofthelimbs.Thematurepeptideofthisproteinisidenticalinallmammalsexaminedincludinghuman,pig,ratandmouse.SUBCELLULARLOCATION:Secretedprotein.TISSUESPECIFICITY:Brainandperipheraltissues.SIMILARITY:BelongstotheNGF-betafamily.
BatchNo.Seeproductlabel
Unitsize500µg
AntigenRecombinanthumanNT3
OtherNamesNeurotrophin-3;Neurotrophicfactor;HDNF;Nervegrowthfactor2;NGF-2;Ntf3;Ntf-3
AccessionNT3_HUMAN
ProducedinSheep
PurityProteinGpurifiedIgG
ApplicationsIHC,ELISA,WB,inhibitionofBIOLOGicalactivity.Aconcentrationof1-10µg/mlisrecommendedforIHC,ELISA,WBandinhibitionofbiologicalactivityinvitro;2-10µg/ml(ED50)forinvivouse.ThisantiserumwillneutraliseNT3butnototherneurotrophins.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityAcrossreactivityoflessthan1%tomouseNGF,recombinanthumanBDNFand5%toNT4/5hasbeenshownby1-siteELISA.
Cross-reactivityThisantiserumisknowntoreactwithrat,chickenandhumanNT3.
BlastitIfyouwouldliketoseethesharedidentitybetweendifferentspeciesorotherproteinsfollowthelinkinAccessionfield,selectthenthesequence(makesurethatyouareselectingthesequencethatyouareinterestedin,asthesequencemaybetheprecursorratherthanthematureproteinforexample)andcopyandpasteitHEREandblast/formatit.
FormLyophilised
ReconstitutionReconstitutein500µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchase
References1.Zouhetal.(1996)Mol.Neurobio.13(3):185-97
2.Rushetal.(1997)Clin.Exp.Pharmacol.24:549-55
3.Tafreshietal.(1998)Neurosci.83(2):373-80
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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