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当前位置: 首页 > 产品中心 > Functional_antibody > Biosensis/Mouse monoclonal antibody to human Gremlin-1 [4C2]: IgG/M-877-100/100 µg
商品详细Biosensis/Mouse monoclonal antibody to human Gremlin-1 [4C2]: IgG/M-877-100/100 µg
Biosensis/Mouse monoclonal antibody to human Gremlin-1 [4C2]: IgG/M-877-100/100 µg
Biosensis/Mouse monoclonal antibody to human Gremlin-1 [4C2]: IgG/M-877-100/100 µg
商品编号: M-877-100
品牌: Biosensis inc
市场价: ¥6540.00
美元价: 3924.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
Gremlin-1isasecretedcytokinethatmayplayaroleduringcarcinogenesisandmetanephrickidneyorganogenesis,asaBMPantagoNISTrequiredforearlylimboutgrowthandpatterninginmaintainingtheFGF4-SHHfeedbackloop.Itdown-regulatestheBMP4signalinginadose-dependentmanner.Italsoactsasinhibitorofmonocytechemotaxis.Itishighlyexpressedinsmallintestine,fetalbrainandcolon.Weaklyexpressedinbrain,ovary,prostate,pancreasandskeletalmuscle.Inbrainfoundintheregionlocalizedaroundtheinternalcapsuleinthelargesubcorticalnuclei,includingcaudate,putamen,substantianigra,thalamusandsubthalamus.Predominantlyexpressedinnormalcellsincludingneurons,astrocytesandfibroblasts.Gremlin-1isinducedthroughTGF-beta1-mediatedpathwaysinMesangialcellanditisdown-regulatedintumorcelllines.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenPartialrecombinanthumanGremlin-1(75-184)withaGSTtag.
IsotypeIgG2aKappa
Clone4C2
OtherNamesCysteineknotsuperfamily1BMPantagonist1;Increasedinhighglucoseprotein2;IHG-2;Down-regulatedinMos-transformedcellsprotein;DANdomainfamilymember2;Cellproliferation-inducinggene2proteinGREM1;CKTSF1B1;DAND2;DRM
AccessionGREM1_HUMAN
ProducedinMouse
PurityProteinGpurifiedimmunoglobulin
ApplicationsThisantibodyisrecommendedforWBandsandwichELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen.
Cross-reactivityHuman;
BlastitToseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit.
FormLyophilisedfromPBSpH7.4
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageLyophilisedantibodycanbestoredat-20ºC.Afterreconstitutionkeepaliquotsat-20ºCforhigherstABIlityorat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchase
品牌介绍
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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