Biosensis/人BDNF ELISA试剂盒（2片）/BEK-2002-2P/1 Ea-免疫在线蚂蚁淘旗下平台

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商品详细Biosensis/人BDNF ELISA试剂盒（2片）/BEK-2002-2P/1 Ea

Biosensis/人BDNF ELISA试剂盒（2片）/BEK-2002-2P/1 Ea

商品编号： BEK-2002-2P

品牌： Biosensis inc

市场价： ¥15940.00

美元价： 9564.00

产地：美国(厂家直采)

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产品分类：夹心法ELISA

公司分类： Sandwich_method_ELISA

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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	Find a 1 plate size of this product here. Enquire about bulk discounts for ten or more plates, at sales@biosensis.com
Description	Try our new BDNF Rapid ELISA kit (BEK-2211-2P). Same specificity and sensitivity, but faster! The human BDNF Kit is a sandwich ELISA. The capture antibody is a monoclonal BDNF antibody pre-coated onto the 96-well strip plates provided in the kit. Human test samples and standards of known BDNF concentration are added to these wells and allowed to complex with the bound BNDF antibody. A biotinylated BDNF antibody is then added. This detection antibody binds to the antigen thus completing the sandwich. After washing, an enzyme Avidin-Biotin-Peroxidase complex (ABC) is added which binds to the second antibody. The peroxidase substrate TMB is added to induce a coloured reaction product. The intensity of this coloured product is directly proportional to the concentration of BDNF present in the samples. The purpose of this kit is the in-vitro quantitative determination of human BDNF in samples such as sera, plasma and cell culture supernates. This kit has been configured for research use only and is not to be used in diagnostic or clinical procedures.
Batch No.	See product labels
Antigen	BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. Post Translation Modification (PTM): The propeptide is N-glycosylated and glycosulfated. PTM: Converted into mature BDNF by plasmin (PLG) (By similarity). DISEASE: Defects in BDNF are a cause of congenital central hypoventilation syndrome (CCHS); also known as congenital failure of autonomic control or Ondine curse. CCHS is a rare disorder characterized by abnormal control of respiration in the absence of neuromuscular or lung disease, or an identifiable brain stem lesion. A deficiency in autonomic control of respiration results in inadequate or negligible ventilatory and arousal responses to hypercapnia and hypoxemia. CCHS is frequently complicated with neurocristopathies such as Hirschsprung disease that occurs in about 16% of CCHS cases. SIMILARITY: Belongs to the NGF-beta family.
Other Names	Brain-derived neurotrophic factor; BDNF; Abrineurin
Accession	P23560 BDNF_HUMAN;
Produced in	The standard and immunogen for this kit is recombinant BDNF produced in and purified from an insect cell (sf21) expression system. This protein sequence is identical in human, mouse, rat, and many other species.
Specificity	Human; Mouse; Rat;
Storage	Store at 4°C
Specific References	Morichi S. et al (2016) Examination of neurological prognostic markers in patients with respiratory syncytial virus-associated encephalopathy.Int J Neurosci. 2016 Feb;1:1-6 Morichi S. et al (2014) Brain-derived neurotrophic factor and interleukin-6 levels in the serum and cerebrospinal fluid of children with viral infection-induced encephalopathy.Neurochem Res. 2014 Nov;39(11):2143-9. Valvassori SS. et al (2014) Sodium butyrate functions as an antidepressant and improves cognition with enhanced neurotrophic expression in models of maternal deprivation and chronic mild stress.Curr Neurovasc Res. 2014;11(4):359-66. Khan, Zarghona A (2012) Ph.D Thesis, Biochemical Markers as Evidence of the Effects of Environmental Enrichment on Physiological Processes in Huntingtons Disease Patients, Edith Cowan University, Western Australia. Morichi S. et al (2012) Expressions of brain-derived neurotrophic factor (BDNF) in cerebrospinal fluid and plasma of children with meningitis and encephalitis/encephalopathy.Int J Neurosci. 2012 Aug 20
Kit components	The ELISA kit box contains 2 x 96 pre-coated strip plates, protein standards, detection reagents, substrate buffer and precise instructions.
Range	31.2 pg/ml - 2,000 pg/ml
Sensitivity	< 15 pg/ml
Kit protocol	BEK-2002-2P_as_at_Jan2017_protocol.pdf

品牌介绍

Biosensis是一家由生命科学家和商业团队组成的公司，致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验，并在生命科学研究和诊断市场的生命科学抗体，试剂和试剂盒的商业化方面拥有50多年的经验。

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电话：PE-1239-5 神经肽和受体 B-100-PS型受体和通道分子 2个平板ELISA试剂盒 M-1763-100英尺 TR-200-BGT公司电话：PE-1239-2 PE-1242-5型 M-1249-100号神经营养因子受体细胞周期调节器 S-1759-100号 PE-1606-100型 PE-1762-100型 B-200-PS型 PE-019-100型 PE-1241-5型 PE-003-100 1个平板ELISA试剂盒 BL-003-1000型 PE-1246-2型感觉神经系统 PE-1253-100型 TR-100-FJ BL-005-500型神经内分泌 M-1728-100型 DNA损伤与修复 PE-001-100型 PE-1608-1型 TR-400-AG公司 PE-1243-25 细胞标记 PE-1608-5型 TR-100-FJT 自噬 PE-1242-2型其他神经元神经递质和酶抗氧化酶神经元标志物标记抗体 BL-004-500型 PE-019-25 PE-1608-10型 BL-002-1250型受体体嵌合体信令与转录基质和粘附分子 BL-001-1250型癌症 PE-019-500 干细胞连接蛋白 TR-300-AG型细胞凋亡 PE-1252-100型生长因子发展阿尔茨海默氏症/帕金森氏症

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