Biosensis/Amylo-Glo RTD Amyloid Plaque Stain Reagent/TR-300-AG/1 Ea-免疫在线蚂蚁淘旗下平台

cancer官网 cellgs报价 cellbiologics代购 cellntec采购 db_biotech正品 diagnostic清关 etonbio everest exbio ez Stemgent产品 polysciences荧光物质 Biosensis价格美国Avanti Oxon华东代理 Labvision厂家 CCT代理蚂蚁淘 Iduron,Inc.

免责声明：

本站有部分内容来自互联网，如无意中侵犯了某个媒体、公司、企业或个人等的知识产权，请来电或致函告之，
本网站将在规定时间内给予删除等相关处理。

扫描二维码关注官方微信

获取最新促销及产品信息

Description	Amylo-Glo®RTDReadytoDiluteStainingreagentisdesignedtostainamyloidplaquesintissuesections.ThisnovelMarkerhasseveraladvantagesoverotherconventionalmarkerssuchasThioflavinSandCongoRedbecauseofitsuniquechemicalandspectralproperties.(L.Schmuedetal.(2012)J.NeuroscienceMethods209:120126).UsingAmylo-Glo®resultsinaverybrightblueUVexcitablestainunderphysiologicalconditionsthatwillnotbleedthroughwhenIlluminatedwithotherfilters.Itsbrightnessmakesitidealforlowmagnificationquantificationstudies,whileitsuniqueexcitation/emissionprofileandmildstainingconditionsmakesitidealforcombinationformultipleimmunofluorescentlabelingstudies.Amylo-Glo®RTDiscompatIBLewithfresh,frozen,andformalin-fixedimmunohistochemistryorcytochemistry,anditisparticularlygoodforconfocalandmultiplelabelingbecauseofitshighfluorescentintensityandhighresistancetophoto-bleaching.MoreoverbecauseAmylo-Glo®fluorescesintheUVchannel,doubleandtriplelabelingexperimentscanbeperformedveryeasily(seeprotocol).
Relatedproducts	Amylo-Glo/EBkitcatalognumberTR-400-AG
BatchNo.	Seeviallabel
OtherNames	AmyloGlo
CompoundName	Compound:Amylo-Glo;Classification:Styrylbenzenederivative;Appearance:Yellowsolution;MolecularWeight:392;Filtersystemforvisualizing:UV
Purity	Thinlayerchromatographyusingaluminaplatesandasolventsystemofethanolandwater(3:1)revealedthepresenceoftwofluorescentisomers.Noamountofstartingmaterialwasdetected.
Applications	Stainingofamyloidplaquesinhumanandanimaltissues,seeincludedprotocol
Specificity	amyloidplaquesbothintraneuronalandvascular
Appearance	ExcitationPeak:334;EmissionPeak:533nm-unbound,438nmwhenboundtoamyloid.TovisualizeAmylo-glointissue,UVlightisrequired.Forexample,Amylo-GlotissuecanbeexaminedusinganepifluoresentmicroscopewithUV(NikonUV-2A)filtercube.Excitation(325-375nm)Emission(400-450nm)istypical.Alsonote,itisnotuncommonforAmylo-Glotoappearlightyellowwhenexaminedbyeye,yetappearalightbluecolorwhenphotographed.
Reconstitution	Readytodiluteperprotocol;100X
Storage	Thestocksolutioncanbestoredforupto6monthsafterdateofreceiptat4°Cprotectedfromlight.Nopreservatives.Usesteriletechniquewhenhandlingandproperlaboratoryprocedures.
ExpiryDate	6monthsfromdateofpurchase
SpecificReferences	AbudEM(2017)"GenerationofHumanMicrogliafromInducedPluripotentStemCellstoStudyInnateImmunityinNeurologicalDiseases."PhDThesis.2017;Application:IFSpecies:Mouse AbudEMetal.(2017)"iPSC-DerivedHumanMicroglia-likeCellstoStudyNeurologicalDiseases."Neuron.2017;49(2):278-93Application:IFSpecies:Mouse SolomonIHetal.(2017)"Brainandliverpathology,amyloiddeposition,andinterferonresponsesamongolderHIV-positivepatientsinthelateHAARTera."BMCInfectDis.2017;17(1):151Application:IFSpecies:Human XuFetal.(2016)"Cerebralvascularamyloidseedsdriveamyloidβ-proteinfibrilassemblywithadistinctanti-parallelstructure."NatCommun.2016;7:13527.Application:IFSpecies:Mouse KatsouriLetal.(2016)"PPARγ-coactivator-1αgenetransferreducesneuronallossandamyloid-βgenerationbyreducingβ-secretaseinanAlzheimersdiseasemodel."ProcNatlAcadSciUSA.2016;113(43):12292-97.Application:IFSpecies:Mouse EspositoGetal.(2016)"Autologoustransplantationofintestine-isolatedgliacellsimprovesneuropathologyandrestorescognitivedeficitsinβamyloid-inducedneurodegeneration."SciRep.2016;6:22605.Application:IFSpecies:Rat MarshSEetal.(2016)"TheadaptiveimmunesystemrestrainsAlzheimer"sdiseasepathogenesisbymodulatingmicroglialfunction."ProcNatlSciUSA.Feb16.pii:201525466.Application:IFSpecies:HuFibrillaramyloidvisualization. KimYHetal.(2015)"A3DhumanneuralcellculturesystemformodelingAlzheimer"sdisease."NatProtoc.Jul;10(7):985-1006.Application:IFSpecies:Hu,Humanneuralstem-cell-derivedthree-dimensional(3D)culturesystem. NijholtDAetal.(2015)"PregnancyZoneProteinisIncreasedintheAlzheimer"sDiseaseBrainandAssociateswithSenilePlaques."JAlzheimer"sDisease.46(1):227-38.Application:IFSpecies:Hu KamphuisWetal.(2015)"GFAPandvimentindeficiencyaltersgeneexpressioninastrocytesandmicrogliainwild-typemiceandchangesthetranscriptionalresponseofreactivegliainmousemodelforAlzheimer"sdisease."Glia.Jun;63(6):1036-56.Application:IFSpecies:Mouse ChoiSHetal.(2014)"Athree-dimensionalhumanneuralcellculturemodelofAlzheimer"sdisease."NatureOct12.doi:10.1038/nature1380.Application:IFSpecies:Hu,Humanneuralstem-cell-derivedthree-dimensional(3D)culturesystem. NiedowiczDMetal.(2014)."Obesityanddiabetescausecognitivedysfunctionintheabsenceofacceleratedbeta-amyloiddepositioninanovelmurinemodelofmixedorvasculardementia."ActaNeuropatholCommun.2014Jun10;2:64.
GeneralReferences	L.Schmuedetal.(2012)J.NeuroscienceMethods209:120126
KitComponents	5mLof100XAmylo-GloRTD(A-GRTD)solution
ReagentKitprotocol	TR-300-AG_as_at_Apr2014_protocol.pdf
MSDS	MSDS_TR-300-AG_as_at_July2015.pdf